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6119-70-6 Quinine sulfate dihydrate Quinine sulfate dihydrate Price
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Product Name:Quinine Sulphate
CAS No:60-93-5
EINECS No:205-003-2
Color:White crystalline powder
Purity:99%
Quinine sulphate is an alkaloid of cinchona that was once widely used to control and prevent malaria; it also has analgesic, antipyretic, mild oxytocic, cardiac depressant, and sclerosing properties, and it decreases the excitability of the motor end plate. It is used as the dihydrochloride, hydrochloride, or sulfate salt in the treatment of resistant falciparum malaria.
Quinine suphate occurs naturally in the bark of the cinchona tree, though it has also been synthesized in the laboratory. The medicinal properties of the cinchona tree were originally discovered by the Quechua, who are indigenous to Peru and Bolivia; later, the Jesuits were the first to bring cinchona to Europe.
Quinine sulphate can cause abnormal heart rhythms, and should be avoided if possible in patients with atrial fibrillation, conduction defects or heart block. Quinine can cause hemolysis in G6PD deficiency (an inherited deficiency), but this risk is small and the physician should not hesitate to use quinine in patients with G6PD deficiency when there is no alternative.
Test Item |
Specifications |
Result |
Characteristics |
White or light yellow crystalline powder |
White crystalline powder |
Infrared Spectrum Appraisal |
Should comply |
Match up the reference |
Specific Optical Rotation |
158 °~ 168°(Ethanol) |
161° |
Melting Point |
173℃ ~ 178℃ |
174℃ ~ 177℃ |
Loss on Drying |
≤1.0% |
0.7% |
Residue on Ignition |
≤0.1% |
0.06% |
Heavy metal |
<10ppm |
Conforms |
Sulphate |
<500ppm |
Conforms |
Chloride |
<250ppm |
Conforms |
Other Cinchona Alkaloid |
<1.0% |
0.3% |
Assase Total Base |
C20H24N2O2>98% |
99.2% |
CAS NO:30123-17-2
CAS NO:171596-29-5
CAS NO:171596-29-5
CAS NO:171596-29-5
CAS NO:171596-29-5
CAS NO:171596-29-5
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