4-Chlorophenol

Details:

General

P-Chlorophenol is a highly effective Preservatives and Bactericides，Pharmaceutical Intermediate，Pesticide Intermediate，Dye and Pigment Intermediate           

CAS Number 106 - 48 - 9

 

Physical Properties

Physical form  White crystalline solid

 

Odo:  In its pure state, it has a distinctive odor. This odor is somewhat similar to the pungent smell of phenol, yet is distinct due to the presence of the chlorine atom. It is generally described as having a slight medicinal or phenolic odor.

Melting and Boiling Points: Its melting point ranges from is 62 - 65 °C. When it melts, the water temperature should be above 70 °C.  This means that within this temperature range, solid p - chlorophenol gradually transforms into a liquid state. Its boiling point is around 217 - 219 °C. When this boiling point is reached, liquid p - chlorophenol vaporizes into a gaseous state. These temperature parameters are of great significance for controlling the state of p - chlorophenol during storage, transportation, and use.

Solubility: p - Chlorophenol has a relatively low solubility in water and is classified as a slightly soluble substance. However, it exhibits good solubility in some organic solvents such as ethanol, ether, and benzene. For example, in ethanol, it can dissolve relatively easily under certain temperature conditions. This property enables it to play a corresponding role in chemical reactions or solution formulations using ethanol as a solvent.

 

 

Specifications

Test Item	Standard Values
Appearance	White crystalline solid
P-chlorophenol(GC)	≥99.50%
O-chlorophenol(GC)	≤0.10%
Phenol	≤0.20%
2,6-Dichlorophenol	≤0.30%
2,4-Dichlorophenol	≤0.20%
2,4,6-trichlorophenol	≤0.10%
Maximum Other Single Impurities	≤0.10%
Water Content	≤0.2%

 

Applications  

Preservatives and Bactericides

 

p - Chlorophenol (CAS No. 106 - 48 - 9) is widely used in the fields of preservatives and bactericides. It has a remarkable inhibitory and killing effect on microorganisms such as bacteria and fungi. In terms of wood preservation, applying p - chlorophenol preparations to the wood surface or allowing the wood to absorb it through soaking can effectively prevent the wood from being eroded by microorganisms like mold and decay - causing fungi, thus extending the service life of the wood.

In industrial circulating water systems, it can be used as a bactericide to inhibit the growth and reproduction of bacteria and algae in the water, preventing the formation of biological fouling and ensuring the normal operation of the circulating water system. For example, in the circulating water system of the paper - making industry, adding an appropriate amount of p - chlorophenol can reduce the corrosion of equipment and pipelines by microorganisms.

Pharmaceutical Intermediate

p - Chlorophenol is an important intermediate for the synthesis of various drugs. For instance, in the synthesis of some non - steroidal anti - inflammatory drugs, it can serve as a starting material or a key intermediate. The chlorine atom and phenolic hydroxyl group in its chemical structure can be introduced or transformed into other functional groups through a series of chemical reactions such as substitution reactions and condensation reactions, thereby constructing drug molecules with specific pharmacological activities.

Meanwhile, it is also used in the synthesis of antifungal drugs. The chlorine atom and phenolic hydroxyl group in its structure endow the molecule with certain antifungal activity. Through further chemical modification, more efficient antifungal drugs can be obtained.

Pesticide Intermediate

p - Chlorophenol plays a crucial role in the synthesis of pesticides. It can be used to produce organophosphorus insecticides and bactericides, etc. For example, in the synthesis of some organophosphorus pesticides with good insecticidal activity, p - chlorophenol is required to provide specific chemical structural parts. These structural parts help the pesticides bind to the enzymes or receptors in pests, thus exerting an insecticidal effect.

p - Chlorophenol can also be used in the synthesis of herbicides. By modifying its chemical structure and introducing other active groups, it can interfere with the physiological processes of weeds, such as inhibiting the photosynthesis or protein synthesis of weeds, thereby achieving the purpose of weed control.

Dye and Pigment Intermediate

As a dye and pigment intermediate, p - Chlorophenol can participate in the synthesis of various dyes with bright colors and good dyeing properties. Through chemical reactions, chromophores and auxochromes can be introduced into its structure, thus synthesizing dyes for dyeing materials such as textiles and leather.
In terms of pigment synthesis, p - Chlorophenol can be used to manufacture high - performance organic pigments. These pigments have good light resistance, weather resistance, and color stability, and can be used for coloring industrial products such as plastics and coatings.