74863-84-6 Argatroban Argatroban Price
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Description
Argatroban is a peptidomimetic small molecule direct thrombin inhibitor (DTI), functional as an anticoagulant agent. Thrombin
is responsible for activating many factors and proteins in the coagulation response pathway, and inhibition of thrombin
activity curbs this response and restricts formation of clots. Direct thrombin inhibition has been described to
protect against thrombosis by limiting the formation of clots inside blood vessels.
Specification
Test Items |
Specification |
Results |
Description |
White to off white crystalline powder |
Comply |
Melting point |
166-170°C |
167.3-168.1°C |
Identification |
Positive reaction |
Positive reaction |
Related substances |
≤1.0% |
0.16% |
Loss on drying |
≤0.5% |
0.06% |
Residue on ignition |
≤0.1% |
0.02% |
Chloride |
≤0.014% |
<0.014 |
Heavy Metals |
≤20ppm |
<20ppm |
Clarity of solution |
Conform to standard |
Complies |
Microbial Limit |
≤20ppm |
<20ppm |
Assay |
≥99.0% |
99.12% |
Usage
Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. Argatroban is used as an anticoagulant in
individuals with thrombosis and heparin induced thrombocytopenia.
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