135062-02-1 Repaglinide Repaglinide Price
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Repaglinide 135062-02-1 APIS made in China:
Introduction:
Repaglinide lowers blood glucose by stimulating the release of insulin from the pancreas. It achieves this by closing ATP-dependent potassium channels in the membrane of the beta cells. This depolarizes the beta cells, opening the cells' calcium channels, and the resulting calcium influx induces insulin secretion.
Other name: 4-Ethoxycarbonyl-3-ethoxy phenyl acetic acid; (S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonylmethyl]benzoic acid; 2-ethoxy-4-[2-({3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl}amino)-2-oxoethyl]benzoic acid; 2-ethoxy-4-[2-({(1S)-3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl}amino)-2-oxoethyl]benzoic acid
CAS NO.: 135062-02-1
MF: C27H36N2O4
MW: 452.5857
InChI: 1/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7,10-13,17,19,23H,4-5,8-9,14-16,18H2,1-3H3,(H,28,30)(H,31,32)/t23-/m0/s1
Melting point: 129-130°C
Boiling point: 672.9°C at 760 mmHg
Flash point: 360.8°C
Density: 1.137g/cm3
Standard: USP/BP/CP/EP
Odor: odorless
Specification for API:
ITEMS |
SPECIFICATION |
Appearance |
White or off white powder |
Identification |
|
--IR |
Similar to standard |
--HPLC |
Similar to standard |
Water |
NMT 2.00% |
Residue on ignition |
NMT 0.1% |
Heavy metals |
NMT 0.001% |
Assay (HPLC) |
NLT98.0% and NMT102.0% Calculated on the anhydrous basis |
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