143491-57-0 Emtricitabine hydrate Emtricitabine Price
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Factory Supply Antiretroviral Emtricitabine 143491-57-0 |
Product name: emtricitabine
Alias:SM-Q;4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-(2r-cis)-2(1h)-pyrimidinone;(-)-BETA-2',3'-DIDEOXY-5-FLUORO-3'-THIACYTIDINE;EMTRITABINE;FUMITREMORGIN C;EMTRICITABIN;4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
CAS No.: 143491-57-0
Molecular Weight: 247.2467
Molecular Formula: C8H10FN3O3S
Item |
Requirements |
Test Results |
Description |
A white or almost white crystalline powder |
white crystalline powder |
Solubility |
Freely soluble in Methanol and Water; Practically insoluble in Dichloromethane |
Complies |
Identification |
The infrared absorption spectrum is concordant with the spectrum obtained from Emtricitabine RS or with the reference spectrum of Emtricitabine |
Complies |
|
Determine the Specific Optical Rotation using a 2.5 mg/ml solution in water R and calculate with reference to the dried substance; [α]D20 °C = -105.0° to -115.0°. |
-107.5° |
Limit of Emtricitabine Enantiomer |
≤0.30% |
Not detected |
Loss on Drying |
≤0.5% (3 hours at 105°C) |
0.14% |
Residue on Ignition |
≤0.1% |
Complies |
Related Substance |
Any impurity before the principal Peak ≤0.5% |
Complies |
|
Not more than 2 impurities over 0.1% before the principal peak |
Complies |
|
Any impurity after the principal peak ≤0.7% |
Complies |
|
Not more than 2 impurities over 0.1% after the principal peak |
Complies |
|
Total impurities ≤1.0% |
0.10% |
Residual Solvents |
Ethanol ≤0.30% |
0.14% |
|
Dichloromethane ≤ 0.06% |
Not detected |
|
DMF ≤ 0.088% |
Not detected |
|
Triethylamine ≤ 0.032% |
Not detected |
|
Toluene NMT 0.089% |
Not detected |
Heavy Metals |
≤20ppm |
Complies |
Assay |
99.0% - 101.0% |
100.1% |
Conclusion |
Meets the Requirements |
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