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70359-46-5 Brimonidine D-tartrate Brimonidine D-tartrate Price
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Product name: Brimonidine Tartrate
Other name: BriMonidine D-tartrate
Specification: 99%min
CAS : 70359-46-5
Color : white or off white powder
Molecular formula: C15H16BrN5O6
MW : 442.2214
Grade : Pharma grade
Basic Information
ITEMS |
SPECIFICATION |
RESULTS |
Appearance |
Off-white or slight yellow crystalline powder |
Conforms |
Solubility |
Sparingly soluble in water, insoluble in methanol, acetone |
Conforms |
Identification a) IR b) Retention time(HPLC) |
Conforms to standard Conforms to standard |
Conforms Conforms |
Appearance of solution |
The solution is not more opalescent than reference suspension I and not more intensely colored than reference solution Y7(1 in 10 carbon dioxide-free water R ) |
conforms |
Melting Point |
204-209ºC |
205.3-207.2 ºC |
PH
|
3-4 (i in 10 carbon dioxide-free water R) |
3.2 |
Loss on drying |
≤0.5%at 100ºC to the constant weight |
0.04% |
Sulphated Ash |
≤0.1% |
0.01% |
Heavy metals |
≤20ppm |
<20ppm |
Related substances
|
Single impurities≤0.5% Total impurity≤1.0% |
0.08% 0.15% |
Residual solvents |
Ethanol: ≤ 0.5%; Acetone:≤ 0.5% |
Conforms |
Specific Rotation |
+9.0° to +10.5° |
+9.8° |
Purity |
99.0-101.0%(C11H10Br5.C4H6O6) ( on dry basis) |
99.85% |
CONCLUSION: |
The product complies with enterprise standard |
Brimonidine is a drug used to treat open-angle glaucoma or ocular hypertension.
It acts via decreasing synthesis of aqueous humor, and increasing the amount that drains from the eye through uveoscleral outflow. As a treatment for glaucoma, it is usually given in eyedrop form.
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