53714-56-0 Leuprorelin Leuprorelin Price
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Product Name | Leuprorelin |
CAS | 53714-56-0 |
Purity | 98% |
Appearance | White Powder |
MOQ | 250mg |
ITEMS |
SPECIFICATION |
RESULT |
Appearance |
White powder |
Conforms |
Solubility |
Soluble in water or 1% acetic acid at a concentration of ≥1mg/ml to give a clear, colorless solution |
Conforms |
Identity |
A. IR Same with the reference spectrum of Leuprolide B. HPLC Same with the reference solution C. Amino Acid Analysis Ser: Present Glu: 0.85~1.1 Pro: 0.85~1.1 Leu: 1.80~2.2 Tyr: 0.85~1.1 His: 0.85~1.1 Arg: 0.85~1.1 Trp: Present |
Conforms
Conforms
0.84 0.97 1.04 2.02 1.01 0.99 1.00 present |
Specific Optical Rotation |
-38.0~-42.0° [a]20D(c=1,1% HAc) |
-39.2° |
RelatedSubstance (By HPLC) |
Total Impurities(%)≤2.5% acetyl-leuprolide≤1.0% D-His-leuprolide≤0.5% L-Leu6-leuprolide≤0.5% D-Ser-leuprolide≤0.5% Any other Impurity≤0.5% |
0.21% Conforms Conforms Conforms Conforms 0.2% |
Acetate Content(By HPLC) |
4.7~9.0% |
8.7% |
Water Content(Karl Fischer) |
≤5.0% |
1.4% |
Sulphate ash |
≤0.3% |
Conforms |
Bacterial Endotoxins |
≤16.7 IU/mg |
Conforms |
Residual Organic Solvents |
Acetonitrile ≤0.041%(By GC) DMF ≤0.088%(By GC) MEOH ≤0.3%(By GC) TFA ≤0.1%(By HPLC) |
Conforms Conforms Conforms Conforms |
Assay(By Anhydrous, Acetic Acid-free ) |
97.0~103.0% |
98.1.0% |
Leuprorelin, also known as leuprolide, is a manufactured version of a hormone used to treat prostate cancer, breast cancer, endometriosis, uterine fibroids, and early puberty. It is given by injection into a muscle or under the skin.
Leuprorelin was approved for medical use in the United States in 1985. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system
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