117976-90-6 Rebeprazole sodium Rebeprazole sodium Price
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Factory Supply 99% Rabeprazole Sodium powder CAS 117976-90-6 |
Product Name : Rabeprazole Sodium
EINECS NO.: 222-630-7
CAS No.: 117976-90-6
Molecular Formula: C18H20N3NaO3S
Molecular Weight: 381.42
Assay: 99% min HPLC
Appearance: White crystalline powder,easily soluble in ethanol,almost insoluble in water.
Melting point: 140-141°C
Water solubility: insoluble
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome and in combination with amoxicillin and clarithromycin to eradicate Helicobacter pylori.
Certification
Test items |
JP16 |
Imported Drug Registration Standard |
|
Characters |
White to pale yellowish white powder. |
White to pale yellowish white powder. |
|
Solubility |
It is very soluble in water, and freely soluble in ethanol. |
Very soluble in water and methanol, freely soluble in ethanol, practically insoluble in ether. |
|
Identification
|
UV |
Both spectra exhibit similar intensities of absorption at the same wavelengths |
It exhibits maximum absorption at the wavelength of 292nm. |
IR |
Both spectra exhibit similar intensities of absorption at the same wave numbers |
Both spectra exhibit similar intensities of absorption at the same wave numbers |
|
Sodium Salt Reaction |
A solution of Rabeprazole Sodium (1 in 10) responds to the Qualitative Tests <1.09>for sodium salt. |
It responds to the Qualitative Tests for sodium salt. |
|
Chromogenic reaction |
The solution turns to orange. |
|
|
Heavy metals |
Not more than 10ppm |
Not more than 10ppm |
|
Color and clarity of solution |
Not darker than Reference Solution H. |
|
|
Related substances |
Individual impurity <0.1% Total impurities < 1.0% |
Total impurities < 1.5%
|
|
Loss on drying |
Not more than 1.0% |
Not more than 1.0% |
|
Residual solvents |
Dichloromethane<600ppm Acetone < 5000ppm Ethyl Acetate < 5000ppm Anhydrous alcohol<5000ppm
|
Dichloromethane < 600ppm Acetone < 5000ppm Ethyl Acetate < 5000ppm Anhydrous alcohol < 5000ppm
|
|
Assay |
98.0%-101.0% |
Not less than 98.0% |
Functions
Rebeprazole sodium is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions caused by excess stomach acid. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
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