51012-32-9 Tiapride Tiapride Price
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Tiapride is a drug that selectively blocks D2 and D3 dopamine receptors in the brain. It is used to treat a variety of neurological and psychiatric disorders including dyskinesia, alcohol withdrawal syndrome, negative symptoms of psychosis, and agitation and aggression in the elderly. A derivative of benzamide, tiapride is chemically and functionally similar to other benzamide antipsychotics such as sulpiride and amisulpride known for their dopamine antagonist effects.
Certificate of Analysis
Product Name |
Tiapride Hydrochloride |
Other Name |
Tiapride hcl |
|
Purity |
99%min by HPLC |
CAS No. |
|
|
Appearance |
White powder |
M.W. |
3328.42700 |
|
MOQ |
10g |
M.F. |
C15H24N2O4S |
|
Loss on drying |
<3.0% |
Standard |
Factory Standard |
|
Item |
Specification |
Result |
||
Appearance |
White powder |
Complies |
||
Related substance (HPLC) |
Total impurity ≤0.5% Max single impurity ≤0.1% |
0.2% 0.06% |
||
Odor |
Characteristic |
Complies |
||
Assay |
99% |
99.22% |
||
Sieve analysis |
100% pass 80 mesh |
Complies |
||
Heavy Metal |
<10ppm |
Complies |
||
As |
<0.1ppm |
0.05ppm |
||
Pb |
<0.1ppm |
0.05ppm |
||
Cd |
<0.1ppm |
0.05ppm |
||
Residual Solvents |
<100ppm |
Complies |
||
Residual Pesticide |
Negative |
Complies |
||
Total Plate Count |
<1000cfu/g |
Complies |
||
Yeast & Mold |
<100cfu/g |
Complies |
||
E.Coli |
Negative |
Complies |
||
Salmonella |
Negative |
Complies |
Functions
Tiapride Hydrochloride is a kind of benzamide antipsychotics, which has inhibitory effect on the hyperactivity of dopaminergic nerve in the mesencephalic limbic system, and has antagonistic effect on the striatum dopaminergic nerve movement disorder, thus producing a sedative and sedative effect.It is characterized by good effect on sensory motor disease and mental motor behavior disorder.
Animal experiments have shown that Tiapride Hydrochloride can block the conduction of pain impulses through the spinal thalamus to the reticular structure.The analgesic effect of this drug may be related to the hypothalamus's effect on the integration of pain impulse.In addition, there are antiemetic effects
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