(R)-7-(benzyloxy)- ...

(R)-7-(benzyloxy)- 3,4,12,12a-tetrahydro- 1H-[1,4]oxazino[3,4- c]pyrido[2,1-f][1,2,4]- triazine-6,8-dione

(R)-7-(benzyloxy)- 3,4,12,12a-tetrahydro- 1H-[1,4]oxazino[3,4- c]pyrido[2,1-f][1,2,4]- triazine-6,8-dione

Min.Order / FOB Price:Get Latest Price

100 Kilogram

FOB Price: USD 1.0000

  • Min.Order :100 Kilogram
  • Purity: 98%
  • Payment Terms : L/C,T/T

Keywords

Bictegravir Intermediate 1985607-70-2 (R)-7-(benzyloxy)- 3,4,12,12a-tetrahydro- 1H-[1,4]oxazino[3,4- c]pyrido[2,1-f][1,2,4]- triazine-6,8-dione

Quick Details

  • Appearance:white powder
  • Application:Bictegravir Intermediate
  • PackAge:100g,250g,500g,1kg,25kg.....
  • ProductionCapacity:100|Kilogram|Month
  • Storage:Store at dry and airtight room temperature
  • Transportation:

Superiority:

Bictegravir Intermediate   instock  (We can supply this product in large quantity and the annual output can reach 100kg/month )

 

We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. 

We are committed to provide excellence in researching, manufacturing and drug discovery process.

 

Our research team of scientists consists of western-trained Ph.D.s with experience and capabilities in drug R&D methodologies and medicinal chemistry.

Details:

Description

Baloxavir is an anti-influenza agent extracted from patent WO 2017104691 A1.
IC50 & Target

Influenza virus[1]
Clinical Trial
NCT Number Sponsor Condition Start Date Phase
NCT03653364 Hoffmann-La Roche Influenza December 13, 2018 Phase 3
NCT03629184 Hoffmann-La Roche Influenza December 13, 2018 Phase 3
NCT03684044 Hoffmann-La Roche Influenza November 30, 2018 Phase 3
NCT02954354 Shionogi|Shionogi Inc. Influenza November 1, 2016 Phase 3
NCT02949011 Shionogi|Shionogi Inc. Influenza December 1, 2016 Phase 3
Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (103.41 mM)

* "≥" means soluble, but saturation unknown.

Preparing 
Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 2.0683 mL 10.3415 mL 20.6830 mL
5 mM 0.4137 mL 2.0683 mL 4.1366 mL
10 mM 0.2068 mL 1.0341 mL 2.0683 mL
*Please refer to the solubility information to select the appropriate solvent.
References

 

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