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High Quality Factory outlet Ezetimibe intermediate
High Quality Factory outlet Ezetimibe intermediate
High Quality Factory outlet Ezetimibe intermediate
High Quality Factory outlet Ezetimibe intermediate

High Quality Factory outlet Ezetimibe intermediate

Min.Order / FOB Price:Get Latest Price

1 Gram

FOB Price: USD 1.0000

  • Min.Order :1 Gram
  • Purity: 98% HPLC
  • Payment Terms : L/C,D/A,D/P,T/T,

Keywords

190595-65-4 Factory outlet Ezetimibe intermediate Factory outlet Ezetimibe intermediate Price

Quick Details

  • Appearance:White powder
  • Application:pharmaceutical intermediates
  • PackAge:1kg or 25Kg drum
  • ProductionCapacity:3000|Metric Ton|Year
  • Storage:Store in dry, dark and ventilated place
  • Transportation:By air or by sea. Prompt delivery

Superiority:

 Qingdao Sigma Chemical Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, peptide,Nootropis etc API, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
 
Our Laboratory is located in shandong province. There are 15 experts in our research team. Talented personnel and well-equipped laboratory makes rigorous and professional quality control possible. Lyphar Biotech is equipped with various detection devices, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.
 
The aim of QDSIGMA is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
 
QDSIGMA has become the "Top 500 Chinese manufacturing companies","Top 20 of global chemical sales".QDSIGMA has 21 subsidiaries and holding companies.

We promise our customer following items

1.Reasonable price:
2.Low moq:No worry about the low moq, our moq is 1 gram or lower.
3.Good and efficient service,Fast Delivery
4.Super-good quality

Details:

Product Name:Ezetimibe intermediate

CAS:190595-65-4

Molecular formula:C31H25F2NO3

Molecular weight:497.53

Properties:White  powder

  Ezetimibe is a new class of selective cholesterol absorption inhibitors, which can inhibit the absorption of cholesterol from the small intestine by binding to the intestinal brush-like marginal vesicle superior membrane protein (relative molecular weight 145X103), and reduce the cholesterol content in serum and liver. Unlike cholic acid mixture, ezetimibe did not affect the absorption of cholesterol esters, other steroids (such as bovine cholic acid), triacylglycerol and fat-soluble vitamins. Its pharmacological effect has nothing to do with the inhibition of acetyl-coenzyme A-cholesterol acetyltransferase (ACAT) and the expression of LDL receptor (scavenger receptor). After absorption, ezetimibe was bound to glucuronic acid in the liver and circulated through the liver and intestine, and was almost specifically localized in small intestinal mucosal cells.

Specification:

Item Specifications Results
Appearance White  powder Complies
Identification A. IR : Similar to Reference Substance Complies
B. Meets the requirement Complies
Specific Rotation -25°~ -30° -27°
Water Not more than 0.5% 0.10%
Any single other impurity Not more than 0.1% 0.03%
Total impurities Not more than 1.0% 0.10%
Assay 98.5%~102.0% 99.80%
Conclusion The results conforms with enterprise standards

 

 

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