100643-71-8 Desloratadine Desloratadine Price
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CAS Number:100643-71-8
Name:Desloratadine
Formula:C19H19ClN2
Molecular Weight:310.82
Synonyms:Neoclarityn;Opulis;Sch 34117;5H-Benzo[5,6]cyclohepta[1,2-b]pyridine,8-chloro-6,11-dihydro-11-(4-piperidinylidene)-;8-Chloro-11-(4-piperidylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine;Aerius;Allex;Azomyr;Clarinex;Descarboethoxyloratadine;NSC675447;8-Chloro-6,11-dihydro-11-(4-piperdinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine;
Density:1.221 g/cm3
Melting Point:150-151 °C
Boiling Point:467.9 °C at 760 mmHg
Flash Point:236.8 °C
Solubility:Freely soluble in methanol
Appearance:Beige solid
Tests |
Specifications |
Results |
Characters |
White to off-white crystalline powder with a characteristic sulfide-like order
|
Complies |
Identification |
IR:similar to Reference Standard |
Complies |
Appearance of solution |
Clear and colorless |
Complies |
Specific Rotation |
-127°to -132° |
-131° |
Loss on Drying |
≤0.5% |
0.06% |
Sulphated Ash |
≤0.2% |
0.03% |
Heavy metals |
≤0.002% |
Complies |
pH |
2.0 to 2.6 |
2.3 |
Related Compouds |
|
Undetected Undetected |
Assay(Anhydrous) |
98.0% to 101.5% |
100.2% |
Desloratadine is a tricyclic H1-antihistamine that is used to treat allergies. It is an active metabolite of loratadine.Desloratadine is used to treat allergic rhinitis and nasal congestion.It is the major metabolite of loratadine and the two drugs are similar in safety and effectiveness.Desloratadine is available in many dosage forms and under many trade names worldwide.
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