CasNo.114471-18-0,High Quality Nesiritide acetate,(114471-18-0) Suppliers

1 Gram	FOB Price: USD 1.0000

Min.Order :1 Gram
Purity: 98% HPLC
Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram

Keywords

114471-18-0 Nesiritide acetate Nesiritide acetate Price

Quick Details

Appearance:White powder
Application:pharmaceutical intermediates
PackAge:1kg or 25Kg drum
ProductionCapacity:3000|Metric Ton|Year
Storage:Store in dry, dark and ventilated place
Transportation:By air or by sea. Prompt delivery

Superiority:

Qingdao Sigma Chemical Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, peptide,Nootropis etc API, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

Our Laboratory is located in shandong province. There are 15 experts in our research team. Talented personnel and well-equipped laboratory makes rigorous and professional quality control possible. Lyphar Biotech is equipped with various detection devices, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.

The aim of QDSIGMA is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.

QDSIGMA has become the "Top 500 Chinese manufacturing companies","Top 20 of global chemical sales".QDSIGMA has 21 subsidiaries and holding companies.

We promise our customer following items

1.Reasonable price:
2.Low moq:No worry about the low moq, our moq is 1 gram or lower.
3.Good and efficient service,Fast Delivery
4.Super-good quality

Details:

Specifciation:

1.Competitive price
2.Fast Delivery Within 2 days
3.SGS , BV, GMP,ISO approve
4.Professional factory

Name: Nesiritide Acetate (BNP-32)

Cas No: 114471-18-0(acetate), 132194-29-7(net)

Formula: C143H244N50O42S4

Molecular:3464

Sequence:Ser-Pro-Lys-Met-Val-Gln-Ser-Gly-Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys-Lys-Val-Leu-Arg-His-OH(DISULFIDEBRIDGE:10-26)

Purity:98%

Appearance: white powder

Source: synthetic

Also know as B-Type Natriuretic Peptide, BNP 32, Brain Natriuretic Peptide 32

, Type-B Natriuretic Peptide, Ventricular Natriuretic Peptide, B typ

Functions

Nesiritide acetate is recombinant B-type natriuretic peptide (BNP). BNP is often clinically used as a biomarker for cardiovascular problems like ventricular failure, stroke, and myocardial infarction. Nesiritide exhibits immunosuppressive, anti-inflammatory, and cardioprotective activities. Nesiritide exhibits mixed effects when administered clinically in the treatment of heart failure. Nesiritide decreases CD8+ T cells and levels of TNF-α, IL-1α, and IL-6. This peptide inhibits angiotensin II (ATII)-induced hypertrophy in animal models. Nesiritide suppresses generation of ROS, prevents decreases in the mitochondrial membrane potential, increases levels of Bcl-2, and decreases levels of Bax, inhibiting apoptosis and protecting cardiomyocytes against ischemia/reperfusion-induced injury. The additional diuretic, natriuretic, and vasorelaxant effects of nesiritide are mediated by its binding of the natriuretic peptide receptor A (guanylate cyclase A).

Analysis

ITEM	SPECIFICATION
Appearance:	White crystalline Powder
Assay:	≥99.0%
Heavy Metals	≤10ppm
Arsenic	≤1ppm
Lead	≤3ppm
Mercury	≤0.1ppm
Cadmium	≤1ppm
Total Plate Count	≤1000cfu/g
Yeast & Mold	≤100cfu/g
E.Coli	Negative
Salmonella	Negative