Antiinflammatory agent , Nimesulide CAS:51803-78-2

Antiinflammatory agent , Nimesulide CAS:51803-78-2

Min.Order / FOB Price:Get Latest Price

1 Kilogram	FOB Price:USD 75.0000 -79.0000

1 Kilogram

FOB Price:USD 75.0000 -79.0000

Min.Order :1 Kilogram
Purity: 99.0%
Payment Terms : L/C,D/A,D/P,T/T,

Keywords

Nimesulide 51803-78-2 Etanol-->Dichloromethane-->Acetic acid glacial-->Bromobenzene-->Methanesulfonyl chloride-->Diphenyl oxide

Quick Details

Appearance:Yellow needle-like crystals powder
Application:Labelled Nimesulide (N477500). Antiinflammatory agent.
PackAge: Aluminum foil bag /Fiber drum / as customers' request.
ProductionCapacity:500|Metric Ton|Month
Storage: 2-8°C
Transportation:By air; by sea; or as customers' request.

Superiority:

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present, our customers have spread all over the world, we have rich Transportation experience, we aim to serve customers, to help customers, solve problems for customers. Look forward to working with you!

Details:

Nimesulide is a yellow needle-like crystals powder.It is a non-steroidal anti-inflammatory drug that can be used for pain in chronic arthritis (such as osteoarthritis), surgery and acute post-traumatic pain, and symptomatic treatment of primary dysmenorrhea.

Product Description

Product Name: Nimesulide

CAS: 51803-78-2

MF: C13H12N2O5S

MW: 308.31

EINECS: 257-431-4

Mol File: 51803-78-2.mol

Melting point : 140-146°C

storage temp. : 2-8°C

solubility : Practically insoluble in water, freely soluble in acetone, slightly soluble in anhydrous ethanol.

pka: pKa 6.56± 0.03(H2O,t =25,I=0.02)(Approximate)

Water Solubility : Soluble in water (<50 µg/ml), 1:10 DMSO:PBS (pH 7.2) (<200 µg/ml), ethanol (1 mg/ml), DMSO (15 mg/ml), DMF (15 mg/ml), chloroform, dichloromethane, acetone (freely soluble), and 1N NaOH.

λmax: 391nm(H2O)(lit.)

Merck :14,6548

Stability: Stable. Incompatible with strong oxidizing agents.

Function & Application

Uses1. Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production

Uses2. Labelled Nimesulide (N477500). Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-α production.

Uses3. Antiinflammatory;'Cyclooxygenase 2 inhibitor

Uses4. For the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.

Uses5. Labelled Nimesulide . Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-α production.;Labeled Nimesulide, intended for use as an internal standard

Uses6. Nimesulide is a selective inhibitor of COX-2. The IC50 values are 70 and 1.27 μM for human recombinant COX-1 and -2 (at 20 μM arachidonic acid), respectively, and 22 and 0.03 μM for ovine COX-1 and -2 (at 100 μM arachidonic acid), respectively.[Cayman Chemical]

Certification of Analysis

All Key Manufacturers and Suppliers of Baoji Guokang have routine inspections to ensure they are in compliance with the standards set in place during the original Supplier Assessment Inspection.

Production Inspection Process:

Our Group service includes regular and thorough inspections throughout the manufacturing process, eliminating the need to employ additional quality control inspectors.

- Raw material before any production begins

- Pre-production samples to ensure specifications are being met

- In-process to confirm that standards are maintained

- Pre-shipping to ensure that the product arrives to the customer exactly as expected and is packaged

correctly to prevent any damage in transit.

We can help operating split shipments, meeting the factory minimum quantity but ship them in 2 or 3 shipments with required gaps among. This allows you to move stock through your business without taking up space and capital.

We will arrange the subsequent shipments from our factory to your warehouse.

We can consolidate your small orders from multiple factories, delivering all at the same time to you or your customers,using the most cost-effective route available. At the time of order placement, we will offer details to you about the volume of each component part and what size container will be used.

We can offer the complete package from concept to delivery; arranging everything up until products arrive at your own door or distribution hub.

Delivery can be offered.

- Utilizing your own freight-forwarder

- FOB to a port in China

- CIF to a port near you

Whether you have your own freight-forwarder or you would like to organize shipment; whether you require delivery FOB in China or CIF to a port near you, we are glad to quote and supply whichever way you choose. Please feel free to discuss all options with us.

1.Client is first.We are trying to bring maximum profit to our clients and we only share small.

2.Credibility is the most important.

3.Quality control is our life.

4.Great sense of responsibility.

We will be responsible for not only our products, our clients, our suppliers, also the society.