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198481-33-3 Bazedoxifene Acetate C20H19N5Na2O6
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Pemetrexed disodium Basic information |
Product Name: | Pemetrexed disodium |
Synonyms: | n-[4-[2-(2-amino-4,7-dihydro-4-oxo-1h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid disodium salt;PEMETREXED DISODIUM;PEMETREXED DISODIUM(ALIMTA);PEMETREXED SODIUM;PEMETREXED;2-[4-[2-(4-Amino-2-oxo-3,5,7-triazabicyclo[4.3.0]nona-3,8,10-trien-9-yl)ethyl]benzoyl]aminopentanedioic acid disodium salt;PEMETREXED DISODIUM 99%;PEMETREXED DISODIUM 2.5H2O |
CAS: | 150399-23-8 |
MF: | C20H19N5Na2O6 |
MW: | 471.37 |
EINECS: | 1312995-182-4 |
Product Categories: | Molecular Targeted Antineoplastic;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents;LY-231514 |
Mol File: | 150399-23-8.mol |
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Pemetrexed disodium Chemical Properties |
storage temp. | -20°C Freezer |
CAS DataBase Reference | 150399-23-8(CAS DataBase Reference) |
Safety Information |
Hazard Codes | T;Xi,Xi,T |
Risk Statements | 36/38-60-61-68 |
Safety Statements | 36/37/39-53 |
Chemical Properties | Crystalline Solid |
Uses | Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively |
Uses | Multitargeted antifolate; inhibits thymidylate synthase as well as other folate dependent enzymes. Antineoplastic |
Definition | ChEBI: An organic sodium salt that is the disodium salt of N-{4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid. Inhibits thymidylate synthase (TS), 4 1 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). |
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