Female Steroid Hormones Powder Flibanserin For Hypoactive Sexual Disorder

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Female Steroid Hormones Powder Flibanserin For Hypoactive Sexual 

Disorder CAS 167933-07-5

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A new drug designed to boost sexual desire in women is controversial for some and eagerly awaited by others, but it's hit a potentially serious snag. The drug didn't boost women's desire any more than a placebo in two clinical trials. Flibanserin is called Female Viagra. Flibanserin is a Medical being studied as a non-hormonal treatment for pre-menopausal Female with lacking libido, or a lack of sexual desire. Studies show that about 10-20% of women face hypoactive sexual desire disorder and some say HSDD outnumbers men with sexual problems.Flibanserin is Non-Hormonal, it has no problems associated with other hormonal treatments such as a negative altered mood among other issues.

Flibanserin is the world's first New drug for enhancing female sexuality. It can reduce the amount of 5 - hydroxytryptamine which inhibits sexuality and improve sexual stimulant dopamine levels. It is already submitted to Food and Drug Administration of the United States for approval.

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A new drug designed to boost sexual desire in women is controversial for some and eagerly awaited by others, but it's hit a potentially serious snag. The drug didn't boost women's desire any more than a placebo in two clinical trials.

The Food and Drug Administration posted the clinical trial results on its website today in advance of a committee meeting on Friday, when a panel of experts will vote whether or not to recommend approval of the drug called flibanserin.

Flibanserin is used for hypoactive sexual desire disorder among women. Those receiving flibanserin report a 0.5 increase compared to placebo in the number of times they had “satisfying sexual events”. In those on flibanserin it rose from 2.8 to 4.5 times a month while women receiving placebo reported also an increase of “satisfying sexual events” from 2.7 to 3.7 times a month. The onset of the flibanserin effect was seen from the first timepoint measured after 4 weeks of treatment and maintained throughout the treatment period.

The effectiveness of flibanserin was evaluated in three phase 3 clinical trials. Each of the three trials had two co-primary endpoints, one for satisfying sexual events (SSEs) and the other for sexual desire. Each of the 3 trials also had a secondary endpoint that measured distress related to sexual desire. All three trials showed that flibanserin produced an increase in the number of SSEs and reduced distress related to sexual desire. The first two trials used an electronic diary to measure sexual desire, and did not find an increase. These two trials also measured sexual desire using the Female Sexual Function index (FSFI) as a secondary endpoint, and an increase was observed using this latter measure. The FSFI was used as the co-primary endpoint for sexual desire in the third trial, and again showed a statistically significant increase. Women's overall feeling of improvement was small to none. The overall quality of the evidence was low.

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