83864-78-2 obovatol obovatol Price
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PRODUCT NAME |
Obovatol |
PURITY | HPLC 98% |
MOLECULAR FORMULA | C18H18O3 |
MOLECULAR WEIGHT | 282.3 |
CAS NUMBER |
83864-78-2 |
CHEMICAL FAMILY | Lignanoids |
BIOLOGICAL ACTIVITY |
1. Obovatol has antioxidant, neuroprotective, antiinflammatory, antithrombotic and antitumour effects. 2. Obovatol is a potent NF-κB inhibitors for Alzheimer's disease treatment. 3. Obovatol shows inhibitory effect on the Salmonella type III secretion system, it could be useful for the prevention and supplementary treatment of bacterial infections. 4. Obovatol inhibits the growth and aggressiveness of tongue squamous cell carcinoma through regulation of the EGF-mediated JAK-STAT signaling pathway. 5. Obovatol induces apoptosis via CHOP activation in A549 and H460 NSCLCs. 6. Obovatol inhibits receptor activator of nuclear factor kappa B (NF-κB) ligand (RANKL)-induced osteoclast differentiation in vitro and inflammatory bone loss in vivo, it may be a useful therapeutic agent for the treatment of pathological bone disorders characterized by excessive osteoclastic bone resorption. 7. Obovatol shows neuroprotective effects against glutamate-induced apoptotic stimuli in HT22 cells. 8. Obovatol has a potent antithrombotic effect, which may be due to antiplatelet activity. 9. Obovatol inhibits vascular smooth muscle cell proliferation and intimal hyperplasia by inducing p21Cip1, it may have potential as an anti-proliferative agent for the treatment of restenosis and atherosclerosis. |
STORAGE CONDITIONS | Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.(2-8℃). |
APPLICATIONS | Used to help analyse and resolve the activities of herbal medicines |
PACKAGE | 20mg/bottle;100mg/bottle;1000mg/bottle; |
CAS NO:30123-17-2
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