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95603-44-4 7,10-Bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III 7,10-Bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III Price
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Product Name | 7,10-DiTroc-10-DAB III (CAS95603-44-4) | |||
CAS No. |
95603-44-4 |
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Storage |
Preserve in well-closed, light-resistant containers, and store at room temperature. |
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TEST ITEM |
SPECIFICATION |
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1 |
Appearance |
White or almost white crystalline powder. |
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2 |
Solubility |
Soluble in acetone; soluble in methanol; practically insoluble in water. |
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3 |
Identification |
IR |
The Infrared absorption spectrum of the sample corresponds to that of the reference substance. |
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HPLC |
B. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay. |
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4 |
Specific optical rotation |
-35° to -45° |
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5 |
Bacterial Endotoxins |
≤0.4 EU /mg |
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6 |
Water |
≤1.5% |
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7 |
Residue on Ignition |
≤0.1% |
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8 |
Heavy metals |
≤20ppm |
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9 |
Residual solvents |
Pyridine |
≤200ppm |
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Dichloromethane |
≤600ppm |
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Hexane |
≤290ppm |
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Toluene |
≤890ppm |
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Ethyl acetate |
≤5000ppm |
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Acetic acid |
≤5000ppm |
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Methanol |
≤3000ppm |
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Acetone |
≤5000ppm |
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10 |
Related substances |
10-Deacetyl baccatin |
≤0.15% |
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2-Debenzoxyl 2-pentenoyl docetaxel |
≤0.5% |
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6-Oxodocetaxel |
≤0.3% |
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4-Epidocetaxel |
≤0.3% |
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4-Epi-6-oxodocetaxel |
≤0.2% |
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Any other single impurity |
≤0.10% |
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Total impurities |
≤1.0% |
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11 |
Microbial enumeration |
Total aerobic microbial |
≤100 cfu/g |
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Total molds and yeasts |
≤10 cfu/g |
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Staphylococcus aureus |
Absence |
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Pseudomonas aeruginosa |
Absence |
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Salmonella typhimurium |
Absence |
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Escherichia coli |
Absence |
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12 |
Assay (anhydrous substance and solvent-free) |
97.5% to 102.0% |
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