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50-56-6 Oxytocin Acetate Oxytocin
items |
standard |
result |
appearance |
white powder |
conforms |
solubility |
soluble in water or 1% acetic acid at a concentration of ≥1mg/ml to give a clear, colorless solution |
conforms |
identity by hplc |
the retention is same with the reference substance |
conforms |
amino acid composition |
gly:0.85~1.10 pro:0.85~1.10 leu:0.85~1.10 cys:1.65~2.20 asn:0.85~1.10 gln:0.85~1.10 ile:0.85~1.10 tyr:0.85~1.10 |
1.02 1.06 1.01 1.88 0.96 1.01 0.99 1.02 |
ph |
3.0~6.0 |
5.16 |
specific optical rotation |
c=1,1%hac |
-21.2° |
purity |
≥98.0% |
99.12% |
related substance(by hplc) |
total impurities(%)≤2.0% largest single impurity(%)≤1.0% |
0.88% 0.55% |
acetate content(by hplc) |
≤12.0% |
6.7% |
water |
≤8% |
5.7% |
peptide content (n%) |
≥80.0% |
87.6% |
bacterial endotoxins |
≤70iu/mg |
conforms |
residual organic solvents |
acetonitrile ≤0.041%(by gc) dmf ≤0.088%(by gc) meoh ≤0.3% (by gc) tfa ≤0.1% (by hplc) dcm ≤0.06% (by gc) mecn ≤0.041% (by gc) |
conforms |
assay |
95%~105% |
99.3% |
conclusion |
complies with the standard. |
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