Superiority:
Changzhou Xuanming Chemical Co., Ltd. is dedicated to the technology development, manufacturing, import and export chemicals, which are specialized in pharmaceutical intermediates, pesticide intermediate, industry of fine chemicals and custom synthesis. Now, we enjoy good reputation among customers and take favorable market share in domestic and at abroad.
Changzhou Xuanming Chemical CO., LTD is located in Northern Jiangshu Industry Park, we have modern manufacture bases and some laboratories, which can supply the key intermediate for your projects, and short your synthesis scheme and supply you a reference compound for bioassay or a high purity analytical standard. We have been abided by “treat technology as first, quality as basis, customers as God, and be honest and sincere”. It is our final aim to provide environmental and high technological products and meet customers’ requirements according to keep effors on developing new chemical fields.
Changzhou Xuanming Chemical CO., LTD promises to help you with heart and soul.
Details:
Description
Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and for medical abortions. Types of cancers it is used for include breast cancer, leukemia, lung cancer, lymphoma, and osteosarcoma. Types of autoimmune diseases it is used for include psoriasis, rheumatoid arthritis, and Crohn's disease. It can be given by mouth or by injection.
Common side effects include nausea, feeling tired, fever, increased risk of infection, low white blood cell counts, and breakdown of the skin inside the mouth. Other side effects may include liver disease, lung disease, lymphoma, and severe skin rashes. People on long term treatment should be regularly checked for side effects. It is not safe during breastfeeding. In those with kidney problems lower doses may be needed. It acts by blocking the body's use of folic acid.
Methotrexate was first made in 1947 and came into medical use initially to treat cancer as it was less toxic than other avaliable agents. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. Methotrexate is available as a generic medication. The wholesale cost as of 2014 in the developing world is between 0.06 and 0.36 USD per day for the form taken by mouth. In the United States a typical month of treatment costs 25 to 50 USD.
Properties
Appearance & Physical State: yellow crystalline powder
Density: 1.536 g/cm3
Melting Point: 195ºC
Water Solubility: Insoluble.
Stability: Stable, but light sensitive and hygroscopic. Incompatible with strong acids, strong oxidizing agents. Store at -15C or below.
Storage Condition: -20ºC
Safety Info
RTECS: MA1225000
Hazard Class: 6.1(b)
Safety Statements: S53-S26-S36/37-S45
HS Code: 2933990090
Packing Group: III
WGK Germany: 3
RIDADR: UN 1544
Risk Statements: R61; R25; R36/38
Hazard Codes: T