- Min.Order :1 Gram
- Purity: 98%
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Keywords
CAS 702675-74-9 BX-795 BX 795
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- Application:inhibitor
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BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
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BX795 is a potent and selective inhibitor of PDK1, IKKε and TBK1, which regulates the production of Type 1 interferons during bacterial and viral infection. BX795 blocks the phosphorylation, nuclear translocation, and transcriptional activity of interferon regulatory factor 3 and the production of interferon-β in macrophages stimulated with poly(I:C) or lipopolysaccharide (LPS). BX795 also inhibits ERK8, MAPK-interacting kinase 2, Aurora B, Aurora C, MAP/microtubule affinity-regulating kinases 1-4, TNF receptor associated factor-associated NF-κB activator-binding kinase 1.
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