DAP-81

DAP-81

DAP-81

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1 Gram

Negotiable

  • Min.Order :1 Gram
  • Purity: 98%
  • Payment Terms : L/C

Keywords

cas 794466-17-4 DAP 81 794466-17-4

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  • Appearance:White Solid
  • Application:Inhibitor
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  • ProductionCapacity:1|Kilogram|Month
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BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #

Details:

DAP-81 is a diaminopyrimidine derivative that targets PLKs, destabilizing kinetochore microtubules. Other spindle tubules are stabilized, resulting in monopolar mitotic spindles. In vitro, DAP-81 inhibits Plk1 at an IC50 of 0.9 nM. DAP-81 is currently in ongoing preclinical evaluations.

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