Antidiabetic Pharmaceutical Raw Powders Rosiglitazone CAS 122320-73-4

Details:

Antidiabetic Pharmaceutical Raw Powders Rosiglitazone CAS 122320-73-4


Product Name:Rosiglitazone
Synonyms:5-(4-[2-(METHYL-PYRIDIN-2-YL-AMINO)-ETHOXY]-BENZYL)-THIAZOLIDINE-2,4-DIONE;5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]-phenyl]methyl]-2,4-thiazolidine-dione;AVANDIA;ROSIGLITAZONE;ROSIGLITAZONE HCL;Rosiglitazone free base;Rosiglitazone and its intermediates;ROSIGLITAZONE 99%
CAS:122320-73-4
MF:C18H19N3O3S
MW:357.43
Product Categories:Active Pharmaceutical Ingredients;Rosiglitazone;API's;Inhibitor;
AVANDIA
Melting point: 153-155 C
Storage temp.: 2-8°C
Uses: Antidiabetic .
Uses: A potent and selective PPARγ agonist .


Rosiglitazone Description :

Rosiglitazone is a type of thiazolidinedione antidiabetics. Thiazolidinedione are agonists for peroxisome-proliferator-activated receptor γ (PPAR-γ). PPAR-γ receptors are ligand-activated nuclear transcription factors that modulate gene expression, lowering blood glucose primarily by increasing insulin sensitivity in peripheral tissues . 

Rosiglitazone is widely used to lower blood glucose levels in patients with type 2 diabetes mellitus. Rosiglitazone functionalizes by makes the cells of the body more sensitive to the naturally produced insulin in body. It shouldn't be used if the patient is injecting or inhaling insulin. Using rosiglitazone with insulin could increase the risk of heart failure. Patients having heart failure with symptoms or moderate to severe heart failure should not use Rosiglitazone .

Advantages:

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Antidiabetic Pharmaceutical Raw Powders Rosiglitazone CAS 122320-73-4