HNB Supply Poloxamer Powder CAS 9003-11-6

Details:

English name Poloxamer
Molecular weight 102.13
Molecular formula HO·(C2H4O)m·(C3H6O)n·H
Use as emulsifier and stabilizer

Function and use
1. As emulsifier and stabilizer: Poloxamer188 (Pluronic F68), as an oil-in-water emulsifier, is one of the few synthetic emulsifiers used in intravenous emulsions

2. As a solubilizer: This product can increase the surface solubility of various drugs, such as salicylic acid, diazepam, indomethacin, metronidazole, etc., due to the formation of micelles by surfactants.

3. As an absorption enhancer: on the one hand, this product slows down the peristalsis of the intestines, increases the retention time of the drug in the gastrointestinal tract, and increases the absorption, thereby improving the bioavailability of oral preparations; on the other hand, this product has good compatibility with the skin, Increase skin permeability, can promote the absorption of external drugs.

4 .As a sustained-release material: a solid product with a large molecular weight, used as an adhesive, coating material, etc. to prepare tablets, capsules, gels, etc., to achieve the purpose of sustained and controlled release, and has obtained satisfactory results. Effect. The dosage is 5% to 15%.

5. As a solid dispersant: Pluronic solid product can be used as a solid dispersion carrier, such as phenylbutazone, griseofulvin, digoxin, digoxigenin and the solid dispersion prepared by this product, which greatly improves the performance of the solid dispersion. improve the solubility of these drugs and promote the absorption of these drugs.

[Storage] Stored in a clean, cool and dry area; keep away from strong, direct light.

[Shelf Life] 2 years when properly stored.

[Packing]

Inner double plastic bags--25kg/Fiber drum (35*35*53cm, GW: 28kg, NW: 25kg, 0.06CBM);

Inner double plastic bags--5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg);

Inner double plastic bags--1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).

[Delivery] 5 working days after payment.