Lorcaserin hydrochloride Belviq CAS 856681-05-5

Details:

Lorcaserin hydrochloride Belviq CAS 856681-05-5

Product Description:

Name: 2-chloro-N-(4-chlorophenethyl)propan-1-amine hydrochloride; intermediate of Lorcaserin

CAS: 953789-37-2

Chemical Formula: C11H16Cl3N

Molecular Weight: 268.61

Purity(HPLC): 99.0%

Character: white powder

Introduction:

Lorcaserin hydrochloride is a kind of white solid. Lorcaserin hydrochloride IUPAC name is (R)-1h-3-benzazepine,8-chloro-2,3,4,5-tetrahydro-1-methyl-,hydrochloride. It belongs to APIs. Lorcaserin is the abbreviation of lorcaserin hydrochloride.

Lorcaserin is a kind of Intermediates and named "(±)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride (N-1)". Lorcaserin is a weight-loss drug. It has serotonergic properties and acts as an anorectic. In October 2010, the FDA stated that it could not approve the application for lorcaserin in its present form.

Function and usage:

Lorcaserin is used to help adults who are obese or who are overweight and have weight-related medical problems to lose weight and keep from gaining back that weight. Lorcaserin must be used along with a reduced calorie diet and an exercise plan. Lorcaserin is in a class of medications called serotonin receptor agonists. It works by increasing feelings of fullness so that less food is eaten.

Specification:

ITEMS	SPECIFICATIONS	RESULTS
Description	White Crystalline Powder	White Powder
Identification	Positive	Positive
Assay(by HPLC)	98.0~102.0%	99.64%
Absorbance(E1cm)	465~495	482.5
Melting Point	191~195°C	193.5~195.0°C
Loss On Drying	0.5%max	0.19%
Specific Rotation	+288°~ +298°	+290.2°
Residue On Ignition	0.1%max	0.03%
Related Substances	Total:1.5%max	<1.3%
	Single:0.5%max	<0.4%
Residue Solvents	0.2%max	0.10%
Heavy Metals	20PPm max	<10PPm
Conclusion	The specification conform with enterprise standard.

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