D-Ribose for pharma use

Details:

D-Ribose

Product Profile 

Product Name:  D-Ribose

Synonyms; ribose, pure; D(-)Ribose (1.07605); D(minus)ribose cell culture tested; D-(-)-Ribose

Molecular Formula: C5H10O5

Molecular Weight: 150.1299

CAS Registry Number: 50-69-1

EINECS; 200-059-4

Density: 1.681g/cm3 

Melting point: 88-92℃ 

Boiling point: 375.4°C at 760 mmHg 

Refractive index: 1.612 

Flash point: 180.8°C

Vapour Pressur: 3.6E-07mmHg at 25°C

Intrduction

Ribose is a carbohydrate with the formula C5H10O5; specifically, it is a pentose monosaccharide (simple sugar) with linear form H−(C=O)−(CHOH)4−H, which has all the hydroxyl groups on the same side in the Fischer projection.

The term may refer to either of two enantiomers. The term usually indicates D-ribose, which occurs widely in nature and is discussed here. Its synthetic mirror image, L-ribose, is not found in nature.

D-Ribose was first reported in 1891 by Emil Fischer. It is a C'-2 carbon epimer of the sugar D-arabinose (both isomers of which are named for their source, gum arabic) and ribose itself is named as a partial rearrangement of letters in the word 'arabinose'.

The ribose β-D-ribofuranose forms part of the backbone of RNA. It is related to deoxyribose, which is found in DNA.Phosphorylated derivatives of ribose such as ATP and NADH play central roles in metabolism. cAMP and cGMP, formed from ATP and GTP, serve as secondary messengers in some signalling pathways.

 Function

D-ribose has been widely used as a pharmaceutical intermediate in the manufacturing of riboflavin (VB2), ribofuranosyl, pyran ribose and anti-virus as well as anti-tumor nucleoside drugs. In health care, D-ribose has been used to treat myocardial ischemia, exercise-induced muscle pain and diabetes; in the food industry, D-ribose has been widely used as a natural food sweetener in Japan and other developed countries.    

Certificate of Analysis

Conclusion: The Goods Conform to the standards of AJI97 
Packaging: 25 KG/DRUM 
Storage: Kept in dry, cool, and shaded place with original packaging, avoid moisture, store at room temperature. 
Shelf life: 24 Months