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Thymosin beta 4 acetate Injectable Peptides China supplier for Thymosin beta 4 with competitive price High quality of TB500
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Product Details:
Product name: |
Thymosin beta 4 acetate
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CAS No. |
77591-33-4
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Content |
≥98%
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Appearance |
White crystalline powder |
C212H350N56O78S |
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Molecular weight |
4963.5
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What is TB-500:
TB-500 is an actin-sequestering peptide that modulates inflammation and healing in different tissues. It plays a major role in angiogenesis and tumor metastasis. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y (TMSB4Y). Beta thymosins are a family of proteins which have in common a sequence of about 40 amino acids similar to the small protein thymosin β4.
TB-500 Benefit:
The thymus gland as well as in various localized cells in the human body produces thymosin Beta-4 (TB-4). TB-4 is found in cytoplasm in high levels of concentration as well as in wound fluid. TB-500 is designed to promote the actionable area - the part of TBthat promotes healing. More importantly, manufacturing TB500, despite not being TB4 is possible while the latter is extremely difficult.
TB-500 Dosage:
The ordinary course of treatment is 2.0 or 2.5 mg taken by injection twice per week for 4-6 weeks, followed by monthly or twice-monthly injection of 2.0 or 2.5 mg as needed.
TB-500 Function & Application:
TB-500 is primarily used in the treatment of various muscle injuries or pain caused by inflammation. it is designed to provide the benefits of the naturally occurring thymus produced hormone.
Studies demonstrate that TB-500 is a potent, naturally occurring wound repair factor with anti-inflammatory properties. Tß4 is different from other repair factors, such as growth factors, in that it promotes endothelial and keratinocyte migration. It also does not bind to the extracellular matrix and has a very low molecular weight meaning it can travel relatively long distances through tissues. One of TB-500 key mechanisms of action is its ability to regulate the cell-building protein, Actin, a vital component of cell structure and movement. Of the thousands of proteins present in cells, actin represents up to 10% of the total proteins which therefore plays a major role in the genetic makeup of the cell.
Analysis Specifications :
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TB500 |
GT-A014 |
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Product Name : |
TB500 |
CAS No. : |
77591-33-4 |
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Molecular Formula: |
C212H350N56O78S |
Molecular Weight : |
4963.49 |
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Quantity: |
80g |
Manufacturing |
2018-12-20 |
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Date: |
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Batch NO: |
P180320-A014 |
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Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr |
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Sequence |
-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly |
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-Glu-Ser-OH |
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Store at : |
Cool dry place(-20oC, away from the light) |
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Tests : |
Specifications |
Results |
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Appearance |
White powder |
Conforms |
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Purity(HPLC) |
≥98% |
98.23% |
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Single Impurity (HPLC) |
≤2.0% |
Conforms |
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Peptide Content (N%) |
≥80.0% |
84.1% |
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Water Content (Karl Fischer) |
≤8.0% |
6.0% |
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Acetate Content (HPIC) |
≤12.0% |
7.6% |
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MS (ESI) |
Conforms |
Conforms |
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Mass Balance |
95.0~105.0% |
Conforms |
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Storage:
Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below-18° C.
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