CAS 223673-61-8 Pha...

CAS 223673-61-8 Pharmaceutical Mirabegron For The Treatment Of Overactive Bladder

CAS 223673-61-8 Pharmaceutical Mirabegron For The Treatment Of Overactive Bladder

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Details:

Rivaroxaban
Product name:Rivaroxaban
Other name:draganon;sarpul
CAS No:366789-02-8
Molecular formula:C19H18ClN3O5SMirabegron (Myrbetriq) is a drug for the treatment of overactive bladder. Mirabegron was developed by Astellas Pharma and was approved in the United States in July 2012.

Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity.

Quick View:

Name: Mirabegron
Synonyms: 2-(2-amino-1,3-thiazol-4-yl)-N-(4-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl}phenyl)acetamide; 2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide; Mira veron; N-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenyl)-2-(2-aminothiazol-4-yl)acetamide
MF: C21H24N4O2S
MW: 396.5059
CAS: 223673-61-8
Molecular Structure:


Descriptions:

Myrbetriq is not for everyone. Do not use Myrbetriq if you have an allergy to mirabegron or any ingredients in Myrbetriq. Myrbetriq may cause your blood pressure to increase or make your blood pressure worse if you have a history of high blood pressure. It is recommended that your doctor check your blood pressure while you are taking Myrbetriq. Myrbetriq may increase your chances of not being able to empty your bladder.

Myrbetriq may cause allergic reactions that may be serious. If you experience swelling of the face, lips, throat or tongue, with or without difficulty breathing, stop taking Myrbetriq and tell your doctor right away.

Applications:

Mirabegron's primary use is in the treatment of overactive bladder.

Mirabegron has also recently been shown to activate brown fat and increase metabolism. In a small study of 15 healthy, lean men, Mirabegron was shown to increase basal heart rate, metabolic rate and blood pressure which are signs of cardiovascular stimulation.

Recently, mirabegron was shown to relax in vitro human and rabbit prostatic smooth muscle through activation of β3 adrenoceptor. The same group also showed that mirabegron promotes smooth muscle relaxation by α1 adrenergic receptor blockade.

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