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125-02-0 125-02-0 125-02-0
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Basic Information:
Synonyms: disodium prednisolone 21-phosphate; (11b)-11,17-dihydroxy-21-(phosphonooxy)-pregna-1,4-diene-3,20-dione disodium salt; 1,4-PREGNADIEN-11-BETA, 17,21-TRIOL-3,20-DIONE 21-PHOSPHATE, DISODIUM SALT; SODIUM PREDNISOLONE-21-PHOSPHATE; PREDNISONE SODIUM PHOSPHATE; prednisolone phosphate sodium; PREDNISOLONE SODIUM PHOSPHATE; PREDNISOLONE 21-PHOSPHATE, DISODIUM SALT
CAS: 125-02-0
Molecular formula: C21H27Na2O8P
MW: 484.39
EINECS: 204-722-9
Packing: 5kg/Tin
Quality Standards: USP
Origin: Wuhan, China
Description:
It is a steroid medication used to treat certain types of allergies, inflammatory conditions, autoimmune disorders, and cancers. Some of these conditions include adrenocortical insufficiency, high blood calcium, rheumatoid arthritis, dermatitis, eye inflammation, asthma, andmultiple sclerosis. It is used by mouth, injection into a vein, as a skin cream, and as eye drops.
Side effects with short term use include nausea and feeling tired. More severe side effects include pyschiatric problems, which may occur in about 5% of people. Common side effects with long term use include bone loss, weakness, yeast infections, and easy bruising. While short term use in the later part of pregnancy is safe, use long term or early in early pregnancy is occasionally associated with harm to the baby. It is a glucocorticoid made from hydrocortisone (cortisol).
Technical Analysis
Test item |
Specifications |
Character |
White or almost white crystalline powder |
Specific rotation |
+75 º to +80 º |
Identification |
Complies by IR Complies by TLC |
Chromatographic purity |
Only one principal impurity more than 1.0% and not more than 2.0. other impurity not more than 1.0% |
Loss on drying |
Not more than 0.5% |
≤60ppm |
|
Assay |
97.0% to 102.0% |
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