Details:

Antihistaminic Pharmaceutical White Powder CAS 90729-43-4 Ebastine

Description:

Product Name	Ebastine
Synonyms:	4-(4-benzhydryloxy-1-piperidyl)-1-(4-tert-butylphenyl)butan-1-one;EBASTEL;EBASTIN;EBASTINE;EVASTEL;KESTINE;1-(4-(1,1-dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-buta;1-butanone,1-(4-(1,1-dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidiny
MF	C32H39NO2
MW	469.66
CAS NO	90729-43-4
Molecular structure
Density	1.09g/m3
Melt point	80-82°C
Boiling point	596.3°C at 760 mmHg
Flash point	314.5°C
Vapour Pressure	3.47E-14mmHg at 25°C

Ebastine (trade names Evastin, Kestine, Ebastel, Aleva, Ebatrol) is a H1 antihistamine with low potential for causing drowsiness.

It does not penetrate the blood–brain barrier to a significant amount and thus combines an effective block of theH1 receptor in peripheral tissue with a low incidence of central side effects, i.e. seldom causing sedation or drowsiness.

Function:

Ebastine is a second-generation H1 receptor antagonist that is indicated mainly for allergic rhinitis and chronic idiopathicurticaria. It is available in 10 and 20 mg tablets and as fast-dissolving tablets,as well as in pediatric syrup. It has a recommended flexible daily dose of 10 or 20 mg, depending on disease severity.

In accordance with the basting with cetirizine hydrochloride, loratadine, cetirizine left-handed, imidazole westin is the commonly used several without sedating antihistamines H1 receptor resistance, drug allergy, its characteristic is on the central nervous without sedation or sedation is very small, antihistamines effect is stronger, can significantly inhibited by histamine.

Application:

Clinical main treatment of various allergic diseases such as chronic idiopathic urticaria, seasonal and perennial allergic rhinitis, itchy skin disease. Adult patients with chronic urticaria and allergic rhinitis

Specification: