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White Raw Pharmaceutical Gliquidone Powder for Anti-Diabetic 33342-05-1

White Raw Pharmaceutical Gliquidone Powder for Anti-Diabetic 33342-05-1

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10 Gram

FOB Price:USD 1.0000 -2.0000

  • Min.Order :10 Gram
  • Purity: 99%
  • Payment Terms : L/C

Keywords

33342-05-1 33342-05-1 33342-05-1

Quick Details

  • Appearance:white crystalline powder
  • Application:use in chemical
  • PackAge:bags
  • ProductionCapacity:12|Kilogram|Day
  • Storage:Kept in a well-closed, light-resistant,dry and cool place
  • Transportation:by sea or express

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Details:

White Raw Pharmaceutical Gliquidone Powder for Anti-Diabetic 33342-05-1

Product Name: Gliquidone
Synonyms: ,4-dimethyl-1,3-dioxo-2(1h)-isoquinolinyl)ethyl)-;ardf26;ardf26se;benzenesulfonamide,n-((cyclohexylamino)carbonyl)-4-(2-(3,4-dihydro-7-methoxy-4;GLIQUIDONE;GLIQUIDONE 99%;Gliquidone Tablets;Glurenorm
CAS: 33342-05-1
MF: C27H33N3O6S
MW: 527.63
EINECS: 251-463-2
Product Categories: Active Pharmaceutical Ingredients;API;Glurenorm
MP: 179 °C
Merck: 4443
Appearance : White powders
Usage Antidiabetic.

Introduction:

Gliquidone is an anti-diabetic drug in the sulfonylurea class. In patients with diabetes mellitus, there is a deficiency or absence of a hormone manufactured by the pancreas called insulin. Insulin is the main hormone responsible for the control of sugar in the blood. Gliquidone is an antidiabetic medication which is used in those patients with adult maturity onset or non-insulin dependent diabetes (NIDDM). It works by lowering blood sugar levels by stimulating the production and release of insulin from the pancreas. It also promotes the movement of sugar from the blood into the cells in the body which need it.

Mechanism of Action:

The mechanism of action of gliquidone in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells, and increasing sensitivity of peripheral tissues to insulin. Gliquidone likely binds to ATP-sensitive potassium channel receptors on the pancreatic cell surface, reducing potassium conductance and causing depolarization of the membrane. Membrane depolarization stimulates calcium ion influx through voltage-sensitive calcium channels. This increase in intracellular calcium ion concentration induces the secretion of insulin.


 

White Raw Pharmaceutical Gliquidone Powder for Anti-Diabetic 33342-05-1

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