CAS: 161735-79-1 Sold Best Rasagiline Mesylate High Purity 99%

Details:

CAS: 161735-79-1 Sold Best Rasagiline Mesylate High Purity 99%

Quick Details:

Name:Rasagiline mesylate
CAS Number:161735-79-1
Formula:C12H13N.CH4O3S
Molecular Weight:267.34
Synonyms:R-(+)-Rasagiline mesylate;Methanesulfonic acid;(1R)-N-prop-2-ynyl-2,3-dihydro-1H-inden-1-amine;Rasagiline methanesulfonate;1H-Inden-1-amine, 2,3-dihydro-N-2-propynyl-, (R)-, methanesulfonate;(R)-N-2-Propynyl-1-indanamine methanesulfonate;(R)-N-(prop-2-ynyl)-2,3-dihydro-1H-inden-1-amine methanesulfonate;
Melting Point:155-158 °C
Boiling Point:305.5 °C at 760 mmHg
Flash Point:146.8 °C
Appearance:White to off-white crystalline solid

2.Product Description:

Rasagiline  is an irreversible inhibitor of monoamine oxidase used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.It is selective for MAO type B over type A by a factor of fourteen.

It was developed initially investigated by Prof.Moussa Youdim and Prof.John Finberg of the Faculty of Medicine.

Mechanism of action:Human cells contain two forms of monoamine oxidase, MAO-A and MAO-B.Both are found in the brain, but MAO-B is far more prevalent and is responsible for the breakdown of dopamine after its release into the synapse.Parkinson's disease is characterized by the death of cells that use dopamine to transmit their signals, this results in a decrease in synaptic signal strength and concommitant symptomology.By inhibiting the breakdown of dopamine in the synapse, rasagiline permits the signaling neurons to reabsorb more of it for reuse later, somewhat compensating for the diminished quantities manufactured.