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Muscle Gaining Pharmaceutical Raw Materials Powder Bodybuilding Dapoxetine 98% CAS 119356-77-3
Quick Details:
Product Description:
Product name | Dapoxetine |
Other name | Dapoxetine,d-Dapoxetine; DL-Dapoxetine |
CAS register number | 119356-77-3 |
Molecular formula | C21H23NO.ClH |
Molecular weight | 341.88 |
Molecular structure |
|
Assay | 98% |
Appearance | White to Off-White Cyrstalline Solid |
Package | 25kg/drum or as required |
Usage | can be used as pharmaceutical material |
Minimum order quantity | 25KG |
Shipping | By express courier |
Shipping leading time | Within 12 hours after receiving the payment |
Payment options | , MoneyGram, T/T,Banktransfer |
Price | Negotiated |
Application:
Dapoxetine is a white powder substance and water-soluble. Taken 1–3 hours before sexual activity, it is rapidly absorbed in the body. Its maximum plasma concentration (Cm) is reached 1–2 hours after oral administration.
Randomized, double blind, placebo-controlled trials have confirmed the efficacy of dapoxetine for the treatment of PE.Different dosage has different impacts on different type of PE. Dapoxetine 60 mg significantly improves the mean intravaginal ejaculation latency time (IELT) compared to that of dapoxetine 30 mg in men with lifelong PE, but there is no difference in men with acquired PE. Dapoxetine, given 1–3 hours before sexual episode, prolongs IELT, increases the sense of control and sexual satisfaction in men of 18 to 64 years of age with PE. Since PE is associated with personal distress, interrelationship difficulty, dapoxetine provides help for men with PE to overcome this condition. Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE.
Waldinger’s meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when dapoxetine is used.However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction.[10] Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug’s accumulation in the body, and therefore reducing side effects.
Specification:
Analysis | Specifications | Results |
Appearance | White or almost white crystalline powder | Complies |
Identification | IR | Complies |
Loss on drying | ≤2.0% | 0.5% |
Melting Point | 175°Cto 185°C | 180°C |
Specific rotation | +128°±3° | 183°C+127°C |
Chromatographic impurities | ||
A. Single impurity | ≤0.2% | Complies |
B. Total impurities | ≤0.5% | 0.3% |
Assay | 98.0% to 102.0% | 99.2% |
Conclusion: Conform to the Enterprise standard |
Advantages:
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