Bulk offering first...

Bulk offering first-class Ibrutinib 936563-96-1 supplier

Bulk offering first-class Ibrutinib 936563-96-1 supplier

Min.Order / FOB Price:Get Latest Price

10 Gram

FOB Price:USD 1.0000 -2.0000
  • Min.Order :10 Gram
  • Purity: 99%
  • Payment Terms : L/C

Keywords

bulk offering Ibrutinib bulk offering Ibrutinib bulk offering Ibrutinib

Quick Details

  • Appearance:white crystalline powder
  • Application:use in chemical
  • PackAge:bags
  • ProductionCapacity:12|Kilogram|Day
  • Storage:Kept in a well-closed, light-resistant,dry and cool place
  • Transportation:by sea or express

Superiority:

1,Best Quality:
Our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other countries, and we have got very good feedback from our customers.so you can trust us.
2, Payment method: for example T/T, Westerm Union,other
3, Excellent Service: Best service and after-sales service to all clients.
   1)We will ship the goods within 5days after get your payments.If you want to cancel or change order, please tell me within 24hours after you finish the payment..
   2)We will ship the goods that you order from us by DHL, UPS, TNT and EUB.We will decided to choose which courier depend on different countries.To find the best way to delivery the goods for you.
   3)As usual you can get the goods with in 4-7days.If the goods were lost or not received for other reasons, please contact us immediately.
4,Fast and safe delivery:
Sample Order : As usual you can get the goods within 4-7days. We can send it via HKems, HK Air Post, DHL or other methods.
We have a professional and stable logistics, and we can deliver the package smoothly around 3 to 5 days.
Bulk Order: Shipped via sea or air, it's according to your requirement, delivery time is 7-15days after payment.

We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our customers and principals. With our high-performance teamwork centers and associated production sites for custom synthesis, we ensure effective professional response and offer extensive applications-related consulting and compliance regulation services.

 

Details:




	 



	Bulk offering first-class Ibrutinib 936563-96-1 supplier



	Raw Pharmaceutical 99.9% Purity Ibrutinib For Treat B Cell Cancers CAS 936563-96-1



	 



	Ibrutinib (Imbruvica) is a small molecule drug that binds permanently to a protein, Bruton's tyrosine kinase (BTK), that is important in B cells; the drug is used to treat B cell cancers like mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenström's macroglobulinemia, a form of non-Hodgkin's lymphoma.



	 



	Quick View:



	 



	
		

			
				Product Name
			
				Ibrutinib
		

		

			
				CAS
			
				936563-96-1
		

		

			
				Appearance
			
				White Crystalline Powder
		

		

			
				MF
			
				C25H24N6O2
		

		

			
				MW
			
				440.5
		

		

			
				Purity
			
				99%min
		

		

			
				Application
			
				1.Mantle cell lymphoma (MCL) who have received at least one prior therapy.

				2.Chronic lymphocytic leukemia (CLL) who have received at least one prior therapy.

				3.Waldenstrom's macroglobulinemia.		
		

	




	 



	Descriptions:



	 



	Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.PCI-32765 (Ibrutinib) is a selective and irreversible pyrrolopyrimidine-based inhibitor of BTK with IC50 of 0.5 nM. [1] PCI-32765 binds irreversibly to Cys-481 in BTK and thus is only active with other kinases with such a modifiable cysteine residue. In DOHH2 cells, in which the BCR pathway can be activated by anti-IgG, PCI-32765 inhibits autophosphorylation of BTK (IC50, 11 nM), BTK's physiological substrate, PLCg (IC50, 29 nm), and downstream ERK (IC50, 13 nm).



	 



	Ibrutinib is used to treat chronic lymphocytic leukemia, Waldenstrom's macroglobulinemia, and as a second-line treatment for mantle cell lymphoma, marginal zone lymphoma, and chronic graft vs host disease.



	 



	COA:



	 



	
		

			
				Items
			
				Specifications
			
				Results
		

		

			
				Appearance
			
				White to whitish crystal powder
			
				Conforms
		

		

			
				Loss on drying
			
				NMT 0.5%
			
				0.33%
		

		

			
				Residue on ignition
			
				NMT 0.1%
			
				Conforms
		

		

			
				Heavy metal
			
				NMT 20ppm
			
				Conforms
		

		

			
				Assay (HPLC)
			
				NLT 99.5%
			
				99.77%
		

		

			
				Related substances
			
				NMT 0.5%
			
				0.23%
		

		

			
				Single impurity
			
				NMT 0.1%
			
				0.07%
		

		

			
				Conclusion
			
				Complies to the Enterprise standard.
		

	




                        

                

                

                    View All
                

            

            
            

                Visit Store
            

        


    

        

            
You Might Also Like

            
        

    

        
Related Searches

        
    
        

    

    

        Contact Supplier
    

    

    

    

        
Confirm to collect the product to my collection?

        
OKCancel

    




        

    
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

    
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

    
©2008 LookChem.com,License: ICP 

    
NO.:Zhejiang16009103

    
complaints:service@lookchem.com  Desktop View