Medical KP 103 Efinaconazole CAS 164650-44-6 New Antifungal Raw Material Drugs

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Medical KP 103 Efinaconazole CAS 164650-44-6 New Antifungal Raw Material Drugs

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Efinaconazole Description

Efinaconazole is an emerging antifungal therapy for the topical treatment of onychomycosis. Efinaconazole is an inhibitor of sterol 14α-demethylase and is more effective in vitro than terbinafine, itraconazole, ciclopirox and amorolfine against dermatophytes, yeasts and non-dermatophyte molds.

Efinaconazole is not especially effective, but it is currently the best topical treatment available, with cure rates two or three times better than the next best topical treatment, ciclopirox. It is considered a reasonable option for patients with mild cases, or patients who can not take oral treatment.

Efinaconazole is used for

Treating fungal infections of the toenails.

Efinaconazole is an antifungal. It works by killing or preventing the growth of the fungus.

Do NOT use efinaconazole if

you are allergic to any ingredient in efinaconazole

Contact your doctor or health care provider right away if any of these apply to you.

Efinaconazole Dosing

The dose of efinaconazole will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of efinaconazole. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage form (solution):

For treatment of fungal infection of the toenails:

1. Adults—Apply to the affected toenail(s) once a day for 48 weeks.
2. Children—Use and dose must be determined by your doctor.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Efinaconazole Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Blistering, burning, itching, pain, stinging, or redness at the application site
ingrown toenail

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.