CasNo.235114-32-6,Anti Inflammatory Medicine Micafungin / Micafungin-d11 CAS: 235114-32-6 Powder,(235114-32-6) Suppliers

10 Gram	FOB Price:USD 1.0000 -2.0000

Min.Order :10 Gram
Purity: 99%
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Keywords

235114-32-6 235114-32-6 235114-32-6

Quick Details

Appearance:white crystalline powder
Application:use in chemical
PackAge:bags
ProductionCapacity:12|Kilogram|Day
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Details:

Anti Inflammatory Medicine Micafungin / Micafungin-d11 CAS: 235114-32-6 Powder

Quick detail

Product Name:	Micafungin
Synonyms:	MICAFUNGIN;Micafungin (Acid);PneuMocandin A0,1-[(4R,5R)-4,5-dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]-;Micafungin-d11
CAS:	235114-32-6
MF:	C56H71N9O23S
MW:	1270.28
EINECS:
Product Categories:	Antifungals;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API

Micafungin Introduction

Micafungin (trade name Mycamine) is an echinocandin antifungal drug developed by Astellas Pharma. It inhibits the production of beta-1,3-glucan, an essential component of fungal cell walls. Micafungin is administered intravenously. It received final approval from the U.S. Food and Drug Administration on March 16, 2005, and gained approval in the European Union on April 25, 2008.

Micafungin is a semi-synthetic cyclic lipopeptide belonging to the echinocandin class that was reported in 1999 from Fujisawa in Japan. Unlike other marketed semi-synthetic derivatives in this class, micafungin is not derived from echinocandin but rather from FR901379 which contains a phenolic sulfate to enhance aqueous solubility, a serious limitation in the class. Micafungin inhibits the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi and is extensively referenced in the literature with over 700 citations.

Medical Application API

Usage

An echinocandin antifungal drug which inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections.

Usage

Micafungin is a semi-synthetic cyclic lipopeptide belonging to the echinocandin class that was reported in 1999 from Fujisawa in Japan. Unlike other marketed semi-synthetic derivatives in this class, micafungin is not derived from echinocandin but rather from FR901379 which contains a phenolic sulphate to enhance aqueous solubility, a serious limitation in the class. Micafungin inhibits the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi and is extensively referenced in the literature with over 700 citations.