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Safe Oral Topical Ointment Dyclonine Hydrochloride Raw Material Drugs CAS 536-43-6
Quick detail
Name: | Dyclonine Hydrochloride |
CAS No.: | 536-43-6 |
Formula: | C18H27NO2.HCl |
Molecular Weight: | 325.92 |
Synonyms: | 1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-, hydrochloride (9CI);Propiophenone,4'-butoxy-3-piperidino-, hydrochloride (7CI,8CI);4'-Butoxy-3-piperidinopropiophenone hydrochloride;Diclonina;Diclonine;Dyclothane;Tanaclone; |
EINECS: | 208-633-6 |
Melting Point: | 175-176 °C |
Boiling Point: | 424.5 °C at 760 mmHg |
Flash Point: | 210.5 °C |
Appearance: | White Crystalline Solid |
Safety Info | |
RTECS: | UG8750000 |
Hazard Class: | 6.1(b) |
Safety Statements: | 26-36 |
HS Code: | 2942000000 |
Packing Group: | III |
WGK Germany: | 3 |
RIDADR: | UN 3249 |
Risk Statements: | R22 |
Hazard Codes: | Xn |
Dyclonine Hydrochloride Description
Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. Target: Sodium Channel Dyclonine is an oral anaesthetic that is the active ingredient of Sucrets, an over the counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray.
It is a local anesthetic, used topically as the hydrochloride salt. Dyclonine hydrochloride has been found to possess, in addition to its topical anesthetic properties, significant bactericidal and fungicidal activity. Self-sterilizing action manifested by preparations containing the drug was considerably enhanced upon the addition of chlorobutanol. Results of in vitro tests employing microorganisms commonly involved in local infections indicated that the two agents in combination act synergistically.
Dyclonine Hydrochloride COA
Test Items | Specification | Test Results |
Appearance | white, crystalline, powder | confirm |
Melting point | 172-176℃ | 174℃ |
Chromatographic purity | In Pass | confirm |
Residue on ignition | ≤0.05%% | 0.04% |
Assay | ≥98%% | 99% |
Conclusion | Confirm | Confirm |
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