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9082-07-9 9082-07-9 9082-07-9
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99.8% Purity Chondroitin Sulfate Sodium Salt Powder CAS 9082-07-9
Quick Information:
Product No.:km-759 |
Product Name:Chondroitin sulfate sodium salt(USP36) |
Cas No.:9082-07-9 |
Molecular Formula:C14H22NNaO15S |
Molecular Weight:499.38 |
Product Name: Chondroitin sulfate sodium salt (USP36) Cas No.: 9082-07-9 Molecular formula: C14H22NNaO15S Molecular Weight: 499.38 Appearance: White or yellowish powder Assay: 91.0-105.0% Identification:IR & Significant differential response to sodium PH:5.5-7.5 Clarity and the color of the solution(420nm wavelength):0.35 max Specific rotation(30mg/ml):-20°~-30° Chloride:0.5% max Sulfates:0.24% max Heavy metals: 0.002% max Loss on drying:10.0%max Residue on ignition: 20.0%-30.0% Organic solvent residue: 0.5% max Impurities in electrophoresis: 2.0% max Limit of protein (dry): 6.0% max Total bacterial count: 1000 cfu/g max Mold & Yeast: 100 cfu/g max Salmonella: Negative Escherichia coil: Negative Package: 25kg/fibre drum |
Detailed information:
Chondroitin sulfate is brought to the attention of the Chemical Selection Working Group because it is widely used in dietary supplement that would be consumed over a period of many years to maximize potential beneficial effects. No chronic toxicity studies to support the safety of such long-term use were found in the available literature.
Used with glucosamine, chondroitin sulfate alleviates pain and inflammation from osteoarthritis and reportedly has a beneficial effect on degenerated joints. Thus dietary supplements containing glucosamine and chondroitin sulfate have a potential market of tens of millions of Americans who suffer from osteoarthritis, athletes and dancers who may have joint overuse, and aging baby boomers interested in maintaining their joints.
Chondroitin sulfate is a glycosaminoglycan that functions as a component of proteoglycans. Proteoglycans are found throughout the human body, forming the intricate extracellular matrix. Glycosaminoglycans have also interactive roles in cell-cell recognition and cell growth.
Application:
Chondroitin sulfate is used in a wide variety of areas of research such as bioengineering. Chondroitin sulfate may be used as a biomaterial copolymer or surface derivatization reagent in the development of drug delivery vehicles, tissue engineering devices and bioscaffolds. Chondroitin sulfate may be used for the development of biocompatible structures such as hydrogels, sponges, biofilms, microspheres and micelles.
Chondroitin, a glucosaminoglycan (GAG), is a natural polymer of β-glucuronic acid-(1→ 3)N-acetyl-β-galactosamine [β-GlcA-(1→3)-GalNAc-(1→4)]. Sulfation may occur at the 6-position and/or 4-position of the galactosamine moiety, with the potential of any individual disaccharide unit to be 6-sulfated, 4-sulfated, 4,6-disulfated, or unsulfated.
Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans.
COA:
Items | Standard |
Description | White or light yellow powder |
Solubility | Solution in water, solution in Sodium of Chloride isotonisch 0,9%, practically not solution in ethyl alcohol 96% and choloroform |
Indentification |
Conform to standards spectrum Red to magenta color appear Yellow flame appear |
Transparency of solution | 10% solution should be no more intensively than reference solution |
Assay(CPC) | No Less Than 95% |
Chromaticity of solution | 10% solution should be no more than etalon |
Loss on drying | No more than 10 |
pH | Between 5.0 and 7.0 (5% solution) |
Specific Rotation | Between -18º and -28º (1% solution) |
Heavy Metal | No more than 25PPM |
Residual organic solvents, | Ethnol no more than 1.5% |
Pyrogen | No more than 0.5 eu/mg |
Total Bacteria Count | NMT100CFU/g |
Yeast & Mold | NMT10CFU/g |
Salmonella | Negative |
Staphylococcus aureus | Negative |
Particle size |
100% through 60 mesh |
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