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10 Gram |
FOB Price:USD 1.0000 -2.0000 |
78110-38-0 78110-38-0 78110-38-0
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Aztreonam CAS 78110-38-0 White Crystalline Powder Pharmaceutical Aztreonam
Product Description
Aztreonam (trade names Azactam injection, Cayston inhalation) is a monobactam antibiotic used primarily to treat infections caused by gram-negative bacteria. It is a synthetic drug based on a simpler monobactam isolated from Chromobacterium violaceum. It is resistant to some beta-lactamases, but is inactivated by extended-spectrum beta-lactamases.
It was approved by the U.S. Food and Drug Administration (FDA) in 1986.
Specification
Items | Specification | Analysis Result | |
Appearance | White, odorless crystalline powder | Conform | |
Identification | The retention times of the major peaks in the chromatogram of the assay preparation correspond to those of the Standard preparation obtained in the assay | Conform | |
Color of Solution |
Not more than yellow or greenish- yellow Reference Solution II |
Conform | |
Clarity of solution | Not more than Turbidity Standard I | Conform | |
PH | 4.5~7.5 | 5.2 | |
Related Impurities |
Single impurities | Not more than1.0% | 0.34% |
Total impurities | Not more than3.0% | 1.25% | |
Water Content | Not more than 2.0% | 0.3% | |
Residue of ignition | Not more than 0.1% | Conform | |
Heavy Metals | Not more than 30ppm | Conform | |
Bacterial Endotoxins | Not more than 0.17EU/mg (Aztreonam) | Conform | |
Sterility Test | Sterile (without germs in 14 days) | Conform | |
Particulate matter |
≥10µm, no more than 2500/g ≥25µm, no more than 250/g |
1084 67 |
|
Assay |
Contain C13H17N5O8S2 90.0% ~105.0% (Calculated on anhydrous substance without L-Arginine ) |
99.5% | |
L-Arginine content | 42%~45% |
43.4% |
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