DSIP Acetate GT-A021

Details:

Wuhan Xinru Chemical Industry Co.,Ltd  founded in 2006, engaged in R&D, producing and marketing barium salts, sodium salts, fertilizer and medical intermediates. 
We have several stock-holding factories, based on strong R&D ability, advanced production technology and experienced team; pluses international trade office in Wuhan, we can offer high and stable quality products with quick response and service. 

Since 2006,we have already developed and established a very good relationship with different reputed customers in EU, Egypt, Canada, Korea, USA, Chile, Turkey, Thailand etc.Our products widely used in water purification,magnet material, rubber, ceramic,glass,painting, powder coating, plastic industry, pharmacy and so on. 

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Welcome to our company and warm welcome to inquiry me about all of our products, we will provide the competitive price for it.

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Product details:

Product: DSIP Delta Sleep Inducing Peptide 

CAS #: 62568-57-4
Molecular Formula: C35H48N10O15
Molecular Mass: 848.813620 Da (g/mol)
Amino Acid Sequence: TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU 

Purity: 99.0%

Appearance: White Lyophilized Powder

Acetate content (hpic): ≤15.0%

Mass balance: 95.0~105.0%

Dsip description:

1. Dsip is a neuropeptide found in the hypothalamus, pituitary, and adrenal glands. its isolation has allowed for extensive research which has found several possible primary and peripheral roles of this peptide.

2. first, dsip has been shown to induce sleep. second, it may have benefits as an analgesic in treatment of chronic pain, sometimes as an adjunct treatment. third, dsip has been shown to block acth release and decrease levels of acth, stimulate lh release, and act as an inhibitor of the secretion of somatostatin.

3. the source of production of dsip is yet unknown; it may be produced in the central nervous system or in a peripheral organ. it is thought to pass through the blood-brain barrier (bbb) more easily than most known neuropeptides. as mentioned, dsip has shown positive results in inducing slow-wave eeg (sleep).

4. it has been shown to help treat narcolepsy and restore disturbed sleep patterns to normal sleep rhythms.delta sleep-inducing peptide, abbreviated dsip, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta eeg activity and reduced motor activities.

5. delta sleep-inducing peptide was first discovered in 1974 by the swiss schoenenberger-monnier group who isolated it from the cerebral venous blood of rabbits in an induced state of sleep. it was primarily believed to be involved in sleep regulation due to its apparent ability to induce slow-wave sleep in rabbits, but studies on the subject have been contradictory.
6. dsip is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif: n-trp-ala-gly-gly-asp-ala-ser-gly-glu-c. it has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids.

7. in the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (clip), adrenocorticotrophic hormone (acth), melanocyte-stimulating hormone (msh), thyroid-stimulating hormone (tsh) and melanin concentrating hormone (mch). it is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.

8. in the brain its action may be mediated by nmda receptors. in another study delta sleep-inducing peptide stimulated acetyltransferase activity through α1 receptors in rats.it is unknown where dsip is synthesized.

COA of DSIP:

Applications:

Delta sleep-inducing peptide, abbreviated dsip, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta eeg activity and reduced motor activities.

Many roles for dsip have been suggested following research carried out using peptide analogues with a greater molecular stability and through measuring dsip-like immunological (dsip-li) response by injecting dsip antiserum and antibodies.

Dsip usage:

1. Dsip (delta sleep-inducing peptide) is a neuropeptide found in the hypothalamus, pituitary, and adrenal glands.

2. Its isolation has allowed for extensive research which has found several possible primary and peripheral roles of this peptide.

3. First, dsip has been shown to induce sleep. second, it may have benefits as an analgesic in treatment of chronic pain, sometimes as an adjunct treatment. third, dsip has been shown to block acth release and decrease levels of acth, stimulate lh release, and act as an inhibitor of the secretion of somatostatin.

4. the source of production of dsip is yet unknown; it may be produced in the central nervous system or in a peripheral organ. it is thought to pass. through the blood-brain barrier (bbb) more easily than most known neuropeptides.

5. as mentioned, dsip has shown positive results in inducing slow-wave eeg (sleep).

it has been shown to help treat narcolepsy and restore disturbed sleep patterns to normal sleep rhythms.

Product pictures