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Manufacturer supply melatonin api solubility

Manufacturer supply melatonin api solubility

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1 Metric Ton

FOB Price:USD 5.0000 -10.0000

  • Min.Order :1 Metric Ton
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

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Melatonin 73-31-4 Melatonin 99%

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  • Appearance:powder
  • Application:pharmacetuical,health supplement
  • PackAge:1kg/bag, 25kg/drum
  • ProductionCapacity:1|Metric Ton|Day
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  • Transportation:by express, dhl,tnt,ems by air, by sea

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CAS No.:73-31-4 Latin name: Melatonin

Product Specification: 99% (HPLC)

Active Ingredient: Melatonin

Safety evaluation: innocuous
 
Molecular Formula C13H16N2O2

Molecular Weight 232.2783
 
Melatonin is an indolamine that is produced in the pineal gland. Its chemical appellation is N-Acetyl-5-Methoxytryptamine or C13-H16-N2-O2.

Details:

 

Melatonin is an indoleamine neurohormone found across plants and animals, produced endogenously from serotonin (5-HT) and secreted in animals as a regulatory signal for synchronization of the circadian rhythm and the sleep-wake cycle. The melatonin receptor system, consisting of the MEL-1A-R, MEL-1B-R, and MT3 subtypes, demonstrates particular plasticity and modularity - antagonists such as Luzindole (sc-202700) and 2-Phenylmelatonin (sc-203466) show modification of systemic responses to the Melatonin signal without impeding activation of the receptors by Melatonin. Powerful antioxidant activity is associated with Melatonin, and it is known to provide protection to lipids, proteins, and DNA against oxidative damage. Several antioxidant enzymes are shown to be upregulated by Melatonin, including glutathione peroxidase, superoxide dismutases, and catalase. Melatonin also scavenges free radicals as a terminal antioxidant, reacting to generate stable end products and terminate radical chain reactions. Free movement through the blood-brain barrier positions Melatonin as a particularly significant endogenous antioxidant. Melatonin is a rat NOS1 (nNOS) inhibitor. Melatonin is an activator of MEL-1A-R and MEL-1B-R.

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