Itraconazole CAS ...

Itraconazole CAS NO 84625-61-6

Itraconazole CAS NO 84625-61-6

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84625-61-6 Itraconazole Itraconazole CAS NO 84625-61-6

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  • Appearance:White powder
  • Application:Pharmaceutical intermediates
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  • ProductionCapacity:20000|Kilogram|Day
  • Storage:Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
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Itraconazole   CAS NO 84625-61-6

Details:

 
Itraconazole Basic information
Broad - spectrum antifungal agents Pharmacokinetics Clinical application and indications Dosage and Usage Medicine interactions Clinical evaluation Precautions Drug overdose Chemical properties Uses Production method
Product Name: Itraconazole
Synonyms: SPORANOX;R51211;ORICONAZOLE;TRIASPORIN;-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-2,4-dihyd;3h-1,2,4-triazol-3-one,4-(4-(4-(4-((2-(2,4-dichlorophenyl)-2-(1h-1,2,4-triazol;2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-yl methyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one;4-[4-[4-[4-[[2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]-METHOXY]PHENYL]-1-PIPERAZINYL]PHENYL]-2,4-DIHYDRO-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOL-3-ONE
CAS: 84625-61-6
MF: C35H38Cl2N8O4
MW: 705.63
EINECS: 617-596-9
Product Categories: -;Active Pharmaceutical Ingredients;Antibiotic Explorer;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Antifungal;Metabolite Reference Standard;API Reference Standard Free Base API;Related Substance;API
Mol File: 84625-61-6.mol
Itraconazole Structure
 
Itraconazole Chemical Properties
Melting point  166°C
alpha  -0.1～+0.1°(D/20℃)(c=10,CH2Cl2)
Fp  >110°(230°F)
storage temp.  2-8°C
solubility  chloroform: 50 mg/mL, clear, colorless
form  White powder
pka 3.7(at 25℃)
color  white
Water Solubility  Insoluble in water. Solube in chloroform at 50 mg/ml. Slightly soluble in ethanol or methanol
Merck  14,5245
Stability: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 84625-61-6(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi,Xn,T,F
Risk Statements  36/37/38-36/38-22-39/23/24/25-23/24/25-11
Safety Statements  22-26-36-45-36/37-16
RIDADR  UN 3286 8(6.1)(3) / PGII
WGK Germany  3
RTECS  XZ5481000
Toxicity LD50 (14 day) in mice, rats, dogs (mg/kg): >320, >320, >200 orally (Van Cauteren)
 
 
 
Itraconazole   CAS NO 84625-61-6

 

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