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Chlorpheniramine maleate Chlorpheniramine Chlorpheniramine maleate powder
1.Name:Chlorphenamine Maleate
2.Cas No:113-92-8
3.MF:C16H19ClN2.C4H4O4
4.MW.:390.87
5.Appearance:white crystalline powder
6.Other Names: Chlorphenamine hydrogen maleate; 1-p-Chlorophenyl-1-(2-pyridyl)-3-dime
7.appearance:white crystalline powder
8.meilting point :131.5~135°C
9.Loss on drying: meet therequirment
10.residue on ignition: less than 0.1%
11.Assay: not less than 98.5%
12.usage: Anti-Ulcerative colitis
Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an is chemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemia-reperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.
Xi'an Harmonious Natural Bio-Technology Co., Ltd. was founded in 2010, and located in Xian
International Logistics Industrial Zone, Xi'an City, Shaanxi Province, China. Now it is the
leading researcher and one of the biggest manufacturer in high technology API area.
There are 8 experts in our research team. We insist in innovation and produce high quality
products. And GMP standard workshop and complete stainless extraction equipment.
We have 2 sales departments over 20 people and sell our products all over the world.
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equipped in HNB company, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto
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HNB mainly engaged in export of products including, without limitation, pharmaceutical raw
materials both for vet and human, also Vitamins, Amino Acids, minerals, peptides, plant
extract, feed and food additives.
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