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streptomycin streptomycin powder 57-92-1
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Streptomycin is an aminoglycoside antibiotic. In 1943, Dr. Selman A. Waxman of the University of California, Berkeley and professor of Rutgers University was isolated from Streptomyces. It was the second antibiotic produced and used in clinic after penicillin. Waxman It also won the 1952 Nobel Prize in Physiology or Medicine. Its anti-tuberculosis effect has opened up a new era of tuberculosis treatment. Since then, there is hope that the history of Mycobacterium tuberculosis ravaging human life for thousands of years can be curbed.
Streptomycin is an antibiotic extracted from the culture medium of Streptomyces cinerea. It is an aminoglycoside basic compound, which combines with the ribonucleic acid protein body protein of Mycobacterium tuberculosis to interfere with the protein synthesis of Mycobacterium tuberculosis, thereby killing or inhibiting the growth of Mycobacterium tuberculosis. Because the pain reaction of intramuscular injection of streptomycin is relatively small, it is suitable for clinical use. As long as the application object is properly selected and the dose is appropriate, most patients can be injected for a long time (usually about 2 months). Therefore, it is still the main drug in anti-tuberculosis treatment for decades.
foreign name streptomycin
Chemical formula C21H39N7O12
Molecular weight 581.574
Appearance white amorphous powder
CAS accession number 57-92-1
EINECS accession number 200-355-3
Density 1.98 g/cm³
Melting point 12 ℃
Boiling point 872.9 ℃
Flash point 481.7 ℃
Function
Streptomycin is a microbial source bactericide, which can effectively control plant bacterial diseases, such as apple, pear fire blight, tobacco wildfire, blue mold, cabbage soft rot, tomato bacterial spot rot, late blight, potato seed potato Rot, blackleg, cucumber angular spot, downy mildew, bean downy mildew, bacterial blight, celery bacterial blight, sesame bacterial leaf spot
Streptomycin is an aminoglycoside. Its mechanism of action is to act on ribosomes in bacteria, inhibit bacterial protein synthesis, and destroy the integrity of bacterial cell membranes.
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