2,2-Dimethyl-1,3-dioxane-4,6-dione

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Purity: 98%

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2,2-Dimethyl-1,3-dioxane-4,6-dione 4-[Bis(trimethylsilyl)amino]phenylmagnesium bromide solution ALDRICH

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Application:2,2-Dimethyl-1,3-dioxane-4,6-dione was used in the synthesis of:macrocyclic -keto lactone4-pyridyl-substituted heterocycles2-substituted indolesisofraxidin.
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2,2-Dimethyl-1,3-dioxane-4,6-dione (Meldrum?s acid) is widely used in organic synthesis, especially for multiple C-C bond formations due to its adequate acidity (pKa 4.83) and steric rigidity. Knoevenagel condensation reaction between aldehydes and Meldrum?s acid are accelerated in ionic liquids.