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paracetamol paracetamol powder acetaminophen
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Product Name |
Paracetamol/Acetaminophen |
Appearance |
White or white crystalline powder |
Assay |
99%min |
Test |
HPLC |
Certificate |
ISO 9001 |
CAS |
103-90-2 |
MF |
C17H19N3O3S |
Einecs No |
137-58-6 |
Dosage Form |
Powder |
Storage Temperature |
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. |
Shelf Life |
24 Months |
The Introductction of Paracetamol/Acetaminophen:
Paracetamol(Acetaminophen):
The antipyretic and analgesic acetaminophen, this product is a metabolite of phenacetin, regulates central prostaglandin synthase by inhibiting hypothalamic body temperature. Reduce the synthesis and release of prostaglandin PGE1, bradykinin and histamine. PGE1 mainly acts on the nerve center. Its decrease will lead to a decrease in the central body temperature setting point, and the body surface temperature sensor will feel relatively hot, and then through nerve regulation, it will cause peripheral blood vessels to dilate and sweat to achieve antipyretic effect, which inhibits the central nervous system. The effect of prostaglandin synthesis is similar to that of aspirin, but its anti-inflammatory effect is weak. No effect on platelets and coagulation mechanism. Indications: Used for cold and fever, joint pain, neuralgia, migraine, cancer pain and postoperative pain relief. This product can also be used for patients who are allergic to aspirin, intolerant or not suitable for aspirin (chickenpox, hemophilia and other bleeding disorders, etc.).
The Application & Function of Paracetamol/Acetaminophen:
1. Paracetamol is the most commonly used non-anti-inflammatory antipyretic analgesics, antipyretic effect similar analgesic effect is weak, no anti-inflammatory anti-rheumatic effects, acetanilide drugs is the best varieties. Particularly suitable for patients who can not use carboxylic acids. For cold, toothache embolism. Acetaminophen is also an intermediate for organic synthesis, hydrogen peroxide stabilizer, and photographic chemicals.
2. Paracetamol for antipyretic, analgesic, anti-rheumatic drugs
3. Paracetamol for organic synthesis intermediates, hydrogen peroxide stabilizer, photographic chemicals, non-anti-inflammatory antipyretic analgesics.
The COA of ?Paracetamol/Acetaminophen:
ITEM |
SPECIFICATION |
RESULT |
Appearance |
White, crystalline powder or colorless crystals |
Conforms |
Identification |
Accord With BP2007 |
Conforms |
Assay |
98.5%~101.0% |
99.97% |
Melting point |
75°C~78°C |
77°C |
Optical rotation |
-0.05°~+0.05° |
0.00° |
Heavy metals |
≤ 0.001% |
<0.001% |
Related substances |
||
Impurity B |
≤ 0.3% |
Conforms |
Any other impurity |
≤ 0.3% |
Conforms |
Total of all impurities apart from impurity B |
≤ 0.7% |
Passes |
Impurity F |
≤ 0.1% |
Not detected |
Sulphated ash |
≤ 0.1% |
0.02% |
Appearance of solution |
Accord With BP2007 |
Conforms |
CAS NO:1011529-10-4
CAS NO:51-34-3
CAS NO:77-06-5
CAS NO:51-21-8
CAS NO:56180-94-0
CAS NO:13870-90-1
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