Vecuronium bromide cas:50700-72-6 Vecuronium bromide Vecuronium bromide Vecuronium bromide
Vecuronium bromide
Vecuronium bromide
Vecuronium bromide
Vecuronium bromide
Vecuronium (Norcuron) is a muscle relaxant in the category of non-depolarizing blocking agents. Vecuronium bromide is indicated as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Although vecuronium bromide is often thought of as a muscle relaxant, it may be more accurate to classify it as a paralyzing agent. It is commercially available as ampoules containing 4 or 10 mg of the drug in powder form which needs to be dissolved in distilled water prior to administration to the patient.
Systematic (IUPAC) name | |
---|---|
[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17S)- 17-acetyloxy-10,13-dimethyl-16-(1-methyl-3,4, 5,6-tetrahydro-2H-pyridin-1-yl)-2-(1-piperidyl)- 2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro- 1H-cyclopenta[a]phenanthren-3-yl] acetate |
|
Clinical data | |
AHFS/Drugs.com | monograph |
Pregnancy cat. | C (US) |
Legal status | -only (US) |
Routes | Intravenous |
Pharmacokinetic data | |
Bioavailability | 100% (IV) |
Metabolism | liver 30% |
Half-life | 51–80 minutes (longer with renal failure) |
Excretion | Fecal (40-75%)renal (30% as unchanged drug metabolites) |
Identifiers | |
CAS number | 50700-72-6 |
ATC code | M03AC03 |
PubChem | CID 39765 |
UNII | 7E4PHP5N1D |
ChEMBL | CHEMBL1201219 |
Chemical data | |
Formula | C34H57N2O4+ |
Mol. mass | 557.827 g/mol |
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