Drug peptide Abalop...

Drug peptide Abaloparatide, High purity Peptide cas 247062-33-5 Abaloparatide

Drug peptide Abaloparatide, High purity Peptide cas 247062-33-5 Abaloparatide

Min.Order / FOB Price:Get Latest Price

1 Gram

Negotiable

  • Min.Order :1 Gram
  • Purity: 98% Min
  • Payment Terms : L/C,T/T

Keywords

BA 058 BIM 44058 (Aib29)- Semparatide

Quick Details

  • Appearance:White Lyophilized powder
  • Application:Osteoporosis ,Abaloparatide is an analog of human pTHrP (1-34). It is a potent and selective activator of the parathyroid hormone receptor (PTH1R) signaling pathway and can stimulate bone formation w
  • PackAge:As client's requirements
  • ProductionCapacity:50|Gram|Day
  • Storage:keep sealed and keep from direct light
  • Transportation:Stored in a clean, cool and dry area; keep away from strong, direct light.

Superiority:

Our Advantages:

1.Product Capacity: eptidego has produced thousands of peptides ranging in quantity from milligrams to multiple kilograms with purities up to 99.0%. 

2. Samples free trial:     our company welcome samples to test our quality then make regular orders.

3. Good Service: the company have 24 hours online service and feedback to our clients ontime

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Details:

Introduction

Name:Abaloparatide

Cas No: 247062-33-5

Formula: C174H300N56O49

Molecular:3960.6

Sequence: Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Leu-Aib-Lys-Leu-His-Thr-Ala-NH2

Function

1.Osteoporosis

- not yet an approved application

Application Research

Abaloparatide has shown to induce higher incidences of osteosarcoma in a dose-dependent manner in a 2 year carcinogenicity study with female and male rats. This correlation is not known to be reflected in humans, however patients with increased risk of osteosarcoma including Paget's disease, open epiphyses, and skeletal malignancies should avoid this treatment. Abaloparatide may also cause hypercalcemia so should be avoided in patients with pre-existing conditions of primary hyperthyroidism or hypercalcemia. Overdose is commonly associated with hypercalcemia, nausea, vomiting, dizziness, tachycardia, orthostatic hypotension and headache. There is no known antidote for abaloparatide.

Specifications

Purity (HPLC)

98% min.

Appearance 

White powder

Single Impurity(HPLC) 

1.0%max

Amino Acid Composition 

±10% of theoretical

Peptide Content(N%)

 ≥80.0%

Water Content(Karl Fischer) 

≤8.0%

Acetate Content(HPIC)

≤12.0%

Specific Rotation (20/D) 

-37.0~-47.0°(c=1 1%HAc)

MS(ESI)

 Consistent

Mass Balance 

95.0~105.0%

 

Remarks: The products are restricted in lab research only.

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