CHemwill -- 2,2-Dimethyl-1,3-dioxane-4,6-dione

 

 

CHemwill -- 2,2-Dimethyl-1,3-dioxane-4,6-dione

Meldrum's acid

 

 

Chemical name	Meldrum's acid ；Malonic acid cyclic isopropylidene ester； 2,2-Dimethyl-1,3-dioxane-4,6-dione
CAS	2033-24-1
Molecular formula	C6H8O4
Molecular weight	144.13
Structural formula
Technical index	Item   Index   Appearance   White crystal powder   Specific rotation      Specific rotation      Melting point   92-96°C   Content   >=99%   Boiling point      Density      Refractive index      Solubility
Packing and transportation	Packing specification   Storage   25kg / barrel   Store at room temperature
others	Use:Meropenem series intermediates synthesis

 

Meldrum's acid 2033-24-1

 2,2-Dimethyl-1,3-dioxane-4,6-dione 2033-24-1

99.50% in stock CAS 2033-24-1

 2,2-Dimethyl-1,3-dioxane-4,6-dione CAS 2033-24-1

Meldrum's acid CAS 2033-24-1

 

Name:    2,2-Dimethyl-1,3-dioxane-4,6-dione
Synonyms:    Malonic acid cyclic isopropylidene ester; Meldrum's acid  Isopropyl Malonate;Meldrum’s acid, Malonic acid cyclic isopropylidene ester;2,2-DiMethyl-1,3-dioxane-4,6-dione, 98% 25GR;2,2-Dimethyl-1,3-dioxane-4,6-dione cycl-Isopropylidene Malonate Malonic Acid Cyclic Isopropylidene Ester;2,2-dimethyl-1,3-dioxane-4,6-diacetone;2,2-Dimethyl-4,6-dioxo-m-dioxane;2,2-Dimethyl-m-dioxane-4,6-dione;2,2-dimethyl-m-dioxane-6-dione
CAS:    2033-24-1
MF:    C6H8O4
MW:    144.13
EINECS:    217-992-8
Product Categories:    Heterocycles;Intermediates & Fine Chemicals;-;Dioxanes;Dioxanes & Dioxolanes;Pharmaceuticals;Drug Discovery;pharmaceutical intermediates

Appearance & Physical State     Crystals, white to beige
Melting Point     92-96 °C(lit.)
Water Solubility     2.5 g/100 mL (20 ºC)

2,2-Dimethyl-1,3-dioxane-4,6-dione Chemical Properties
Melting point     92-96 °C(lit.)
Boiling point     182.71°C (rough estimate)
density     1.1311 (rough estimate)
refractive index     1.4434 (estimate)
storage temp.     0-6°C
solubility     dioxane: soluble5%, clear to very slightly hazy, colorless to faintly yellow
pka    5.1(at 25℃)
form     Crystals or Powder
color     Brownish-white to beige-brown
Water Solubility     2.5 g/100 mL (20 ºC)

HazardClass     IRRITANT
HS Code     29322090

2,2-Dimethyl-1,3-dioxane-4,6-dione Usage And Synthesis
Chemical Properties    Crystals, white to beige
Uses    Meldrum`s acid is an intermediate for different organic syntheses. For typical reactions please consult the Meldrum`s acid brochure, which you can order. Contact us. Product Data Sheet
Uses    An antimicrobial agent
Uses    In organic synthesis as a substitute for acyclic malonic esters and generally as a C3O2 synthon.

Preparation Products And Raw materials
Raw materials    Malonic acid
Preparation Products    QUINOLINE-4-BORONIC ACID-->QUINOLINE-4-CARBOXYLIC ACID-->6-BROMO-4-CHLOROQUINOLINE-->4-Bromoquinoline-->4-CHLOROQUINOLINE-->4,7-DIMETHOXY-1,10-PHENANTHROLINE, 97%-->7-DIETHYLAMINO-3-THENOYLCOUMARIN-->4-IODOQUINOLINE-->3-(4-Nitrophenyl)propanoic acid-->6-bromoquinolin-4(3H)-one-->3-(2-THIENYL)PROPIONIC ACID-->3-(4-NITRO-PHENYL)-PROPAN-1-OL

 

 

Chemwill Asia co.,Ltd is one of the leading manufacturer of BIT in CHINA. 

 

Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Basic chemicals , Fine chemicals,  Active pharmaceutical ingredients(APIs), Veterinary,  Indole derivatives, Aromatics, Fluorine, Boronic acids, organocatalysts, chiral building blocks, heterocyclic compounds. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place. 

 

Our R&D team masters core technology for process-design of target building block as well as Tailor-made fine chemicals. Our manufactory specialised in extreme temperature conditions (-100ºC to +300ºC), hydrogenations reaction under high pressure, suzuki coupling reaction, photochemical reaction, Mitsunobu reactions, enantioselective reactions and asymmetric synthesis. 

 

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