Factory Supply Active Pharmaceuticals Ingredients Vitamin B3 Nicotinamide CAS 98-92-0

Superiority:

• description of active pharmaceutical ingredients nicotinamide :

nicotinamide is also called vitamin b3 or vitamin pp, is a kind of water-soluble vitamin, belong to b vitamin, as nad (nicotinamide adenine dinucleotide, nad) and nadp (nicotinamide adenine dinucleotide phosphate, nadp) composition, hydrogenation and dehydrogenation properties of nicotinamide in the body part of this two kinds of structure of coenzyme the reversible, play a role of hydrogen delivery in biological oxidation, can promote tissue respiration, biological oxidation process and the new supersedes the old, having a great significance in maintaining normal tissue, especially the integrity of the skin digestive tract and the nervous system.

this product is mainly used for the prevention and treatment of pellagra, stomatitis, glossitis and so on. in addition, this product has prevention of heart block and improving the sinoatrial node and anti-fast experimental arrhythmia function, can significantly improve vera pammy induced bradycardia and atrioventricular block.

• medical usage of active pharmaceutical ingredients nicotinamide :

1. the same as nicotinic acid, water solubility is better than that of nicotinic acid, but it is easy to form complex with vitamin c and agglomerate. the amount is 30-80mg/kg.

2. nicotinamide and nicotinic acid are mostly the same, nicotinic acid can generate to nicotinamide in animal body. in the absence of nicotinic acid and nicotinamide, you can get pellagra. so they can prevent pellagra. in protein and sugar metabolism,they can play a role, and improve the human and animal nutrition. in addition to using in medicine, but also a large number of them are used as food and feed additive. the world production capacity has more than 3 million tons. in japan, nicotinamide is used in medicine, which accounted for 40%, the feed additives accounted for 50%. food additives accounted for 10%. nicotinamide and nicotinic acid are non-toxic in nature in animal liver, kidney, yeast and rice, sugar, nicotinamide on rat subcutaneous ld50 was 1.7 g / kg.

3. vitamin medicine, which participated in metabolism, is used for the prevention and treatment of pellagra, niacin deficiency.

4.used for skin care, the products can prevent rough skin, maintain the health of the skin cells, promote skin whitening. for the hair, they can promote blood circulation of the scalp, hair follicle health, promote hair growth, and prevent baldness.

5. biochemical studies; tissue culture based nutrition; clinical drug for b vitamins for the prevention and treatment of pellagra and stomatitis, glossitis and other diseases treatment.

6. used for biochemical researches, preparation of tissue culture media , pharmaceutical industry.